DRSC/TRiP Functional Genomics Resources

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Protein Alignment TRAIP and gzl

DIOPT Version :10

Sequence 1:NP_005870.2 Gene:TRAIP / 10293 HGNCID:30764 Length:469 Species:Homo sapiens
Sequence 2:NP_649653.1 Gene:gzl / 40791 FlyBaseID:FBgn0037442 Length:536 Species:Drosophila melanogaster


Alignment Length:121 Identity:26/121 - (21%)
Similarity:42/121 - (34%) Gaps:37/121 - (30%)


- Green bases have known domain annotations that are detailed below.


Human     7 CTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKRTIINKLFFDLAQEEE 71
            |.||.:.|.....:..:.|.|.:|..|:..|. |...|.||.|:.:|                  
  Fly   235 CVICLEDFIEDDKLRVLPCSHPYHTHCIDPWL-TENRRVCPICKRKV------------------ 280

Human    72 NVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGK 127
                  |.|.|.           :..|..|..:|.:.|| ::....::..||:.|:
  Fly   281 ------FTKGEA-----------RASRSRQPSLDNVTDT-DDDTTPLLQQQQSNGR 318

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TRAIPNP_005870.2 RING-H2_TRAIP 6..50 CDD:438143 13/42 (31%)
EnvC 65..>278 CDD:443969 11/63 (17%)
Interaction with CYLD. /evidence=ECO:0000269|PubMed:14676304 211..469
PIP-box. /evidence=ECO:0000269|PubMed:26711499 460..469
gzlNP_649653.1 PA_C_RZF_like 14..171 CDD:239038
RING-H2_RNF13-like 233..278 CDD:438327 14/43 (33%)
Blue background indicates that the domain is not in the aligned region.

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