Protein Alignment TRAIP and Traip

DIOPT Version :10

• Sequence 1: NP_005870.2
• Gene: TRAIP / 10293
• HGNCID: 30764
• Length: 469
• Species: Homo sapiens
• Sequence 2: NP_001102474.1
• Gene: Traip / 367167
• RGDID: 1309761
• Length: 469
• Species: Rattus norvegicus
• Alignment Length: 468
• Identity: 381/468 - (81%)
• Similarity: 420/468 - (89%)
• Gaps: 2/468 - (0%)

Human     1 MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKRTIINKLFFD 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||
  Rat     1 MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKTIINKLFFD 65

Human    66 LAQEEENVLDAEFLKNELDNVRAQLSQKDKEKRDSQVIIDTLRDTLEERNATVVSLQQALGKAEM 130
            ||||||:||||||||||||:::|||||||:||||||.||||||||||||||||.|||.||.||||
  Rat    66 LAQEEESVLDAEFLKNELDSIKAQLSQKDREKRDSQAIIDTLRDTLEERNATVESLQNALNKAEM 130

Human   131 LCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLLQSQRPEVEEMIRDMGVGQSAVE 195
            ||||||||||:||||:||||.||||||:|:|||||||||||||||||.|||||||||||||||||
  Rat   131 LCSTLKKQMKFLEQQRDETKHAQEEARQLKSKMKTMEQIELLLQSQRSEVEEMIRDMGVGQSAVE 195

Human   196 QLAVYCVSLKKEYENLKEARKASGEVADKLRKDLFSSRSKLQTVYSELDQAKLELKSAQKDLQSA 260
            ||||||:||||||||||||||||||:||:|||||.||||||:||.:|||||||||:|||||||||
  Rat   196 QLAVYCISLKKEYENLKEARKASGELADRLRKDLASSRSKLKTVNTELDQAKLELRSAQKDLQSA 260

Human   261 DKEIMSLKKKLTMLQETLNLPPVASETVDRLVLESPAPVE-VNLKLRRPSFRDDIDLNATFDVDT 324
            ||||.||:||||:||.||:||||.||||.|||.||||||| :..:|.||.|.|:|||||||||:|
  Rat   261 DKEITSLRKKLTILQGTLSLPPVTSETVSRLVFESPAPVEMLKPRLHRPPFSDEIDLNATFDVNT 325

Human   325 PPARPSSSQHGYYEKLCLEKSHSPIQDVPKKICKGPRKESQLSLGGQSCAGEPDEELVGAFPIFV 389
            |||:.|||||.:.:|||||::.||:||: .||.|..:.|||||||||.|.|||||||.||||:|:
  Rat   326 PPAQTSSSQHCHPKKLCLERARSPMQDI-LKIPKVSKSESQLSLGGQRCVGEPDEELAGAFPLFI 389

Human   390 RNAILGQKQPKRPRSESSCSKDVVRTGFDGLGGRTKFIQPTDTVMIRPLPVKPKTKVKQRVRVKT 454
            |||:.|||||.|..:||..|.||||.||||||||||||||||..:|||:|||||.|.||:||:||
  Rat   390 RNAVRGQKQPNRTTAESRYSTDVVRIGFDGLGGRTKFIQPTDPTIIRPMPVKPKAKSKQKVRIKT 454

Human   455 VPSLFQAKLDTFL 467
            |.|..|.||||||
  Rat   455 VNSASQPKLDTFL 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRAIP	NP_005870.2	RING-H2_TRAIP	6..50	CDD:438143	43/43 (100%)
		EnvC	65..>278	CDD:443969	185/212 (87%)
		Interaction with CYLD. /evidence=ECO:0000269|PubMed:14676304	211..469		188/258 (73%)
		PIP-box. /evidence=ECO:0000269|PubMed:26711499	460..469		7/8 (88%)
Traip	NP_001102474.1	RING-H2_TRAIP	6..50	CDD:438143	43/43 (100%)
		EnvC	65..>279	CDD:443969	186/213 (87%)