DRSC/TRiP Functional Genomics Resources

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Protein Alignment CDKN2A and NAS6

DIOPT Version :10

Sequence 1:XP_011515977.1 Gene:CDKN2A / 1029 HGNCID:1787 Length:184 Species:Homo sapiens
Sequence 2:NP_011748.3 Gene:NAS6 / 853147 SGDID:S000003464 Length:228 Species:Saccharomyces cerevisiae


Alignment Length:97 Identity:23/97 - (23%)
Similarity:42/97 - (43%) Gaps:13/97 - (13%)


- Green bases have known domain annotations that are detailed below.


Human    81 PVHDAAREG-FLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHAR 144
            |:|.|..|. |.....:||...:.|..:|..||:|:..:......::..:|.        |....
Yeast     5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLL--------SKMEN 61

Human   145 IDAAEGP-SAGWTNLRISKPNCAWHHLEISRS 175
            ::..:.| .:|||...|:   |:..:||:.:|
Yeast    62 VNLDDYPDDSGWTPFHIA---CSVGNLEVVKS 90

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CDKN2AXP_011515977.1 ANKYR <16..148 CDD:440430 14/67 (21%)
ANK repeat 16..42 CDD:293786
ANK repeat 44..74 CDD:293786
ANK repeat 76..108 CDD:293786 8/27 (30%)
NAS6NP_011748.3 ANK repeat 1..33 CDD:293786 8/27 (30%)
ANKYR 3..226 CDD:440430 23/97 (24%)
ANK repeat 35..69 CDD:293786 5/41 (12%)
ANK repeat 71..104 CDD:293786 8/23 (35%)
ANK repeat 107..137 CDD:293786
ANK repeat 139..171 CDD:293786
ANK repeat 173..205 CDD:293786
Blue background indicates that the domain is not in the aligned region.

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