DRSC/TRiP Functional Genomics Resources

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Protein Alignment CDKN2A and cdkn2b

DIOPT Version :10

Sequence 1:XP_011515977.1 Gene:CDKN2A / 1029 HGNCID:1787 Length:184 Species:Homo sapiens
Sequence 2:NP_001006920.1 Gene:cdkn2b / 448767 XenbaseID:XB-GENE-478746 Length:125 Species:Xenopus tropicalis


Alignment Length:108 Identity:62/108 - (57%)
Similarity:79/108 - (73%) Gaps:1/108 - (0%)


- Green bases have known domain annotations that are detailed below.


Human    12 SADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPA 76
            :|:.|.:|.|||.|:..|.:|::|...||.||:||.|||||||||.::|:|||.|||:|...||.
 Frog     4 NANTLCSACARGDVDLARQMLQSGIPVNATNSHGRTPIQVMMMGSPKMAQLLLDHGADPKLPDPC 68

Human    77 TLTRPVHDAAREGFLDTLVVLHRAGARL-DVRDAWGRLPVDLA 118
            |...||||||||||||||:||...||.| :.||.:|:.|:|||
 Frog    69 TGACPVHDAAREGFLDTLLVLLNNGASLYEPRDNFGQRPIDLA 111

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CDKN2AXP_011515977.1 ANKYR <16..148 CDD:440430 61/104 (59%)
ANK repeat 16..42 CDD:293786 11/25 (44%)
ANK repeat 44..74 CDD:293786 19/29 (66%)
ANK repeat 76..108 CDD:293786 20/32 (63%)
cdkn2bNP_001006920.1 ANKYR <6..>111 CDD:440430 59/104 (57%)
ANK repeat 8..34 CDD:293786 11/25 (44%)
ANK repeat 36..66 CDD:293786 19/29 (66%)
ANK repeat 69..94 CDD:293786 17/24 (71%)

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