Protein Alignment CDKN2A and CG44001

DIOPT Version :10

• Sequence 1: XP_011515977.1
• Gene: CDKN2A / 1029
• HGNCID: 1787
• Length: 184
• Species: Homo sapiens
• Sequence 2: NP_608900.3
• Gene: CG44001 / 326173
• FlyBaseID: FBgn0264743
• Length: 181
• Species: Drosophila melanogaster
• Alignment Length: 146
• Identity: 42/146 - (28%)
• Similarity: 59/146 - (40%)
• Gaps: 29/146 - (19%)

Human     2 EPAAGSSMEPSAD---WLATAAARGRVEEVRALLEAG-----------ALPNAPNSYGRRPIQVM 52
            :||..:..:...|   |  .||....||.||..::.|           ||..|..: |..||
  Fly    16 QPAQQTLSDMDFDRGIW--NAAIYNEVERVREFIKKGQSMARDDCDYTALHYAARN-GNEPI--- 74

Human    53 MMGSARVAELLLLHG-AEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVD 116
                   .:|||..| |:.|....|..| .:|.||..|.|:.:.:|....|.|.::|..|:..:.
  Fly    75 -------CKLLLDEGKADVNAVTKAGAT-ALHRAAMMGHLEIVKLLVEHKANLLLQDESGQTALH 131

Human   117 LAEELGHRDVARYLRA 132
            .|...||.:|.|.|.|
  Fly   132 RAVMRGHLEVCRILLA 147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKN2A	XP_011515977.1	ANKYR	<16..148	CDD:440430	38/129 (29%)
		ANK repeat	16..42	CDD:293786	10/36 (28%)
		ANK repeat	44..74	CDD:293786	9/30 (30%)
		ANK repeat	76..108	CDD:293786	10/31 (32%)
CG44001	NP_608900.3	ANKYR	<34..>148	CDD:440430	38/126 (30%)
		ANK repeat	61..90	CDD:293786	12/39 (31%)
		ANK repeat	92..123	CDD:293786	10/31 (32%)