Protein Alignment CDKN2A and mlt-3

DIOPT Version :10

• Sequence 1: XP_011515977.1
• Gene: CDKN2A / 1029
• HGNCID: 1787
• Length: 184
• Species: Homo sapiens
• Sequence 2: NP_502319.2
• Gene: mlt-3 / 189743
• WormBaseID: WBGene00012704
• Length: 392
• Species: Caenorhabditis elegans
• Alignment Length: 164
• Identity: 45/164 - (27%)
• Similarity: 66/164 - (40%)
• Gaps: 40/164 - (24%)

Human     6 GSSMEPSAD--W---LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSAR-VAELLL 64
            |:.::.|.:  |   |..|:|.|.:..||.||..||.|...:...|:.|......... |.:.||
 Worm   102 GAKVDDSTESRWQTPLMMASACGNISVVRLLLGRGANPRLCDKEKRQAIHYASSCCQNVVVDTLL 166

Human    65 LHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWG------------------ 111
            ..|.:||.|| :..|.|||:||..|...|.:.|...|..|::::|.|
 Worm   167 AAGCDPNAAD-SEGTTPVHEAAMAGHEITFIALLEKGGNLELKNAKGENAAALACDNNKILQLIS 230

Human   112 ---------------RLPVDLAEELGHRDVARYL 130
                           |.|..|:|.|...|::||:
 Worm   231 EHQAEIAKQSSKTGNRGPRRLSELLEEMDLSRYI 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKN2A	XP_011515977.1	ANKYR	<16..148	CDD:440430	42/149 (28%)
		ANK repeat	16..42	CDD:293786	11/25 (44%)
		ANK repeat	44..74	CDD:293786	8/30 (27%)
		ANK repeat	76..108	CDD:293786	11/31 (35%)
mlt-3	NP_502319.2	ANKYR	38..275	CDD:440430	45/164 (27%)
		ANK repeat	78..109	CDD:293786	1/6 (17%)
		ANK repeat	111..176	CDD:293786	20/64 (31%)
		ANK repeat	178..209	CDD:293786	11/30 (37%)
		SAM_1	248..306	CDD:425739	7/17 (41%)