Protein Alignment CDKN2A and Cdkn2b

DIOPT Version :10

• Sequence 1: XP_011515977.1
• Gene: CDKN2A / 1029
• HGNCID: 1787
• Length: 184
• Species: Homo sapiens
• Sequence 2: NP_031696.1
• Gene: Cdkn2b / 12579
• MGIID: 104737
• Length: 130
• Species: Mus musculus
• Alignment Length: 120
• Identity: 107/120 - (89%)
• Similarity: 111/120 - (92%)
• Gaps: 0/120 - (0%)

Human    16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTR 80
            ||||||||:||.||.||||||.|||.|.:|||||||||||||:||||||||||||||||||||||
Mouse    10 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEPNCADPATLTR 74

Human    81 PVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAG 135
            ||||||||||||||||||||||||||.|||||||||||||.||||:||||.||.|
Mouse    75 PVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYLHAATG 129

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKN2A	XP_011515977.1	ANKYR	<16..148	CDD:440430	107/120 (89%)
		ANK repeat	16..42	CDD:293786	21/25 (84%)
		ANK repeat	44..74	CDD:293786	27/29 (93%)
		ANK repeat	76..108	CDD:293786	31/31 (100%)
Cdkn2b	NP_031696.1	ANK 1	5..34		19/23 (83%)
		ANKYR	<10..130	CDD:440430	107/120 (89%)
		ANK repeat	10..36	CDD:293786	21/25 (84%)
		ANK repeat	38..68	CDD:293786	27/29 (93%)
		ANK 2	38..66		25/27 (93%)
		ANK repeat	70..102	CDD:293786	31/31 (100%)
		ANK 3	71..100		28/28 (100%)
		ANK 4	104..130		22/26 (85%)