DRSC/TRiP Functional Genomics Resources

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Protein Alignment CDKN2A and cdkn2a/b

DIOPT Version :10

Sequence 1:XP_011515977.1 Gene:CDKN2A / 1029 HGNCID:1787 Length:184 Species:Homo sapiens
Sequence 2:XP_002660514.1 Gene:cdkn2a/b / 100329528 ZFINID:ZDB-GENE-081104-306 Length:125 Species:Danio rerio


Alignment Length:117 Identity:56/117 - (47%)
Similarity:74/117 - (63%) Gaps:0/117 - (0%)


- Green bases have known domain annotations that are detailed below.


Human    14 DWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATL 78
            |.|.||||.|.:..|:.||..|...|..|.:.|.||||||||:|.:|.:||..||:||..||.|.
Zfish     6 DELTTAAATGNISHVQFLLSNGVNANVVNKFRRTPIQVMMMGNAPLALVLLEQGADPNVPDPDTG 70

Human    79 TRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130
            :.|:|||||.||:||:.:|.|.||..:.:|.....|||:|::.|:.||...|
Zfish    71 STPLHDAARTGFIDTVRLLIRFGADPNTKDHCDLRPVDVAQQTGNVDVVELL 122

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CDKN2AXP_011515977.1 ANKYR <16..148 CDD:440430 55/115 (48%)
ANK repeat 16..42 CDD:293786 11/25 (44%)
ANK repeat 44..74 CDD:293786 17/29 (59%)
ANK repeat 76..108 CDD:293786 15/31 (48%)
cdkn2a/bXP_002660514.1 ANKYR <8..>122 CDD:440430 54/113 (48%)
ANK repeat 36..66 CDD:293786 17/29 (59%)
ANK repeat 68..100 CDD:293786 15/31 (48%)

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