Protein Alignment CDKN1C and cdkn1ca

DIOPT Version :10

• Sequence 1: NP_000067.1
• Gene: CDKN1C / 1028
• HGNCID: 1786
• Length: 316
• Species: Homo sapiens
• Sequence 2: NP_001002040.1
• Gene: cdkn1ca / 399483
• ZFINID: ZDB-GENE-040123-1
• Length: 212
• Species: Danio rerio
• Alignment Length: 318
• Identity: 80/318 - (25%)
• Similarity: 125/318 - (39%)
• Gaps: 112/318 - (35%)

Human     4 ASLRSTSTMERLVARGTFPVLVRTSACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQD 68
            |::..:|.:||.|||.|||:|.||..||:||||||||||..|::.:|.|::..||:||:::|:.:
Zfish     2 ANVDVSSNLERHVARSTFPLLTRTKVCRNLFGPVDHEELHCEMKRKLQEISERDQSRWNFNFETN 66

Human    69 MPLRGPGRLQWTEVDSDSVPAFYRETVQVGRCRLLLAPRPVAVAVAVSPPLEPAAESLD-GLEEA 132
            .||  ||..:|..:..|::|.||::.||..|.|         .|.:|:...: |:.::| |:..:
Zfish    67 SPL--PGDYEWEAISEDTLPFFYKDKVQNKRAR---------AATSVNATGD-ASSTVDCGISRS 119

Human   133 PEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAA 197
            |....|..||:
Zfish   120 PVAQESEGVPS------------------------------------------------------ 130

Human   198 PAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGA 262
                                               |..||..:.:...::.:||..:...:....
Zfish   131 -----------------------------------RPNEPNQENISGALNSKPARSSVLRNRRKR 160

Human   263 AI----KKLSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTPRKRLR 316
            ::    .:.|.|.|:|||.||||....|...      .|...|....|:|.||||.:|
Zfish   161 SLIPESPRNSTPQITDFFPKRKRVVESKQDE------RSYLQAGTSTSIEVTPRKTIR 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKN1C	NP_000067.1	CDI	33..79	CDD:460503	22/45 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..153		6/29 (21%)
		9 X 4 AA repeats of P-A-P-A	156..213		0/56 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..260		5/78 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..316		13/37 (35%)
		Nuclear localization signal. /evidence=ECO:0000255	278..281		2/2 (100%)
cdkn1ca	NP_001002040.1	CDI	31..76	CDD:460503	22/46 (48%)