Protein Alignment CDKN1C and Cdkn1c

DIOPT Version :10

• Sequence 1: NP_000067.1
• Gene: CDKN1C / 1028
• HGNCID: 1786
• Length: 316
• Species: Homo sapiens
• Sequence 2: NP_001399159.1
• Gene: Cdkn1c / 12577
• MGIID: 104564
• Length: 360
• Species: Mus musculus
• Alignment Length: 194
• Identity: 45/194 - (23%)
• Similarity: 78/194 - (40%)
• Gaps: 54/194 - (27%)

Human    95 ADAHTVPASACLLQMFFIHVFSVMESSVLLAMAFDRAVAICR---PLHYPVILTNGVISKIAVAI 156
            |:..:||...|.:.:.         |.:|||.::..::.:.:   |..:|.::.....|.:.|:.
Mouse    20 ANVASVPDGLCWVSIL---------SCLLLACSYVGSLYVWKSDLPRDHPAVIKRRFTSVLIVSA 75

Human   157 -------AFRCLSLHLPLPILLARM---------PYCRPQVLTHSYCLHPDMARLA--CPEAWGA 203
                   |::..:...|.|.|.|.|         ....|.:||....|.| :.:||  ||  ||.
Mouse    76 LSPVFVWAWKDFTGIQPGPSLFALMGIRLEGLIPAIILPLLLTMVLFLGP-LIQLAMDCP--WGF 137

Human   204 VYSLVVVLSAMVLDPLLIFFSYGLIGRALQGVGSAEDRWKAGQTCAAHLSAVLLF---YIPMIL 264
            :..:.|     |:||  .|:|..|          ::.||...|. .|.|:..|:|   .:||::
Mouse   138 IDGMKV-----VVDP--CFWSLCL----------SDMRWLRNQV-VAPLTEELVFRACMLPMLV 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKN1C	NP_000067.1	CDI	33..79	CDD:460503
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..153		5/31 (16%)
		9 X 4 AA repeats of P-A-P-A	156..213		18/74 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..260		24/83 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..316
		Nuclear localization signal. /evidence=ECO:0000255	278..281
Cdkn1c	NP_001399159.1	CDI	35..81	CDD:460503	8/54 (15%)
		PTZ00341	<197..281	CDD:173534