Protein Alignment CDKN1C and cdknx

DIOPT Version :10

• Sequence 1: NP_000067.1
• Gene: CDKN1C / 1028
• HGNCID: 1786
• Length: 316
• Species: Homo sapiens
• Sequence 2: XP_002934672.1
• Gene: cdknx / 100126686
• XenbaseID: XB-GENE-1032978
• Length: 207
• Species: Xenopus tropicalis
• Alignment Length: 301
• Identity: 75/301 - (24%)
• Similarity: 113/301 - (37%)
• Gaps: 134/301 - (44%)

Human    29 ACRSLFGPVDHEELSRELQARLAELNAEDQNRWDYDFQQDMPLRGPGRLQWTEVDSDSVPAFYRE 93
            |||:||||:||:||..||:.:|.|:.|.|..||::||:...||:  |...|..|:|..||.||.:
 Frog    28 ACRNLFGPIDHDELRSELKRQLKEIQASDCQRWNFDFESGTPLK--GIFCWESVESKDVPTFYSQ 90

Human    94 -------TVQVGRCR--LLLAPRPVAVAVAVSPPLEPAAESLDGLEEAP-EQLPSVPVPAPASTP 148
                   |....|.:  ||::.:|           ||.       |||| :.:.:||.|
 Frog    91 NRSSAANTTTPSRQQQPLLVSRQP-----------EPR-------EEAPLDTVRNVPNP------ 131

Human   149 PPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPA 213
                                                         |.|
 Frog   132 ---------------------------------------------PCA----------------- 134

Human   214 PAPDAAPQESAEQGANQGQRGQEPLADQLHSGISGRPAAGTAAASANGAAIKKLSGPLISDFFAK 278
                   :|:||:...:.|            |:.| ||..:|..|..... ::::.| |:|:|.|
 Frog   135 -------KENAEKTIKRCQ------------GVKG-PAKASAIPSTQHRK-REITTP-ITDYFPK 177

Human   279 RKR---SAPEKSSGDVPAPCPSPSAAPGVGSVEQTPRKRLR 316
            ||:   :.|:.:.| ....||          :||||||::|
 Frog   178 RKKILGAKPDATKG-AHLLCP----------LEQTPRKKIR 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKN1C	NP_000067.1	CDI	33..79	CDD:460503	21/45 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..153		7/29 (24%)
		9 X 4 AA repeats of P-A-P-A	156..213		2/56 (4%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..260		12/78 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..316		13/40 (33%)
		Nuclear localization signal. /evidence=ECO:0000255	278..281		2/2 (100%)
cdknx	XP_002934672.1	CDI	32..77	CDD:460503	21/46 (46%)