Protein Alignment SLC17A2 and dmGlut

DIOPT Version :9

• Sequence 1: NP_001273052.1
• Gene: SLC17A2 / 10246
• HGNCID: 10930
• Length: 478
• Species: Homo sapiens
• Sequence 2: NP_620115.2
• Gene: dmGlut / 47253
• FlyBaseID: FBgn0010497
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 468
• Identity: 146/468 - (31%)
• Similarity: 239/468 - (51%)
• Gaps: 27/468 - (5%)

Human    17 RYGLALIMHFSNFTMITQRVSLSI-AIIAMVNT-TQQQGLSNASTEGPV-ADAFNNSSISIKE-- 76
            ::|::|    |.:.:|.|||.|:| ..:|::|. |.:..||.|.|...| .::.::.|.:|.|
  Fly     6 QWGISL----SRYFVIPQRVILAIMGFLAILNAYTMRVCLSQAITVLVVKKNSTDDDSEAICEPD 66

Human    77 -FDTKASV---YQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFTP 137
             .|...||   ::||.|.||:|.||...|.|:|.||.|.||..||.|..||.|:|.:::.|:.||
  Fly    67 DIDEGTSVGGDFEWSEELQGLILSSFYIGYIVTHIPGGLLAEKFGGKWTLGLGILSTAVFTMLTP 131

Human   138 LAADFG-VILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCVGG 201
            ||.:.| ...:|:.|.:.|:.:|..:.....:.|.|.|..||.||..:...|...|:.:...:.|
  Fly   132 LAINKGDSDWLIVTRVLMGLGEGTTFPALSVLLAAWVPANERGKLGALVLGGGQVGTIMGNLLSG 196

Human   202 LISQALSWPFIFYIFGSTGCVCCLLWFTVI----YDDPMHHPCISVREKEHI---LSSLAQQPSS 259
            :...|..|.|:||.||..|.|    ||.:.    |.||..||.|...|:|::   :.::::....
  Fly   197 VFIDAYGWEFVFYFFGGLGVV----WFAIFMFLCYSDPTSHPFIKPSEREYLVKEIGTISRNEDL 257

Human   260 PGRAVPIKAMVTCLPLWAIFLGFFSHFWLCTIILTYLPTYISTLLHVNIRDSGVLSSLPFIAAAS 324
            |  ..|.||::|.||::|:......|.|...|::|.||.|::.:|..:|:.:|:.||||::....
  Fly   258 P--PTPWKAILTNLPMFALVAAQIGHDWGFYIMVTDLPKYMADVLQFSIKANGLYSSLPYVMMWI 320

Human   325 CTILGGQLADFLLSRNLLRLITVRKLFSSLGLLLPSICAVALPFVASSYVITIILLILIPGTSNL 389
            .::..|.:||:::.|.:|.....||:.:.|....|:|..|...:.....|:.::|..:..|....
  Fly   321 VSVGSGFVADWMIRRGVLSTTNTRKVMTGLAAFGPAIFMVGASYAGCDRVLVVVLFTICMGLMGA 385

Human   390 CDSGFIINTLDIAPRYASFLMGISRGFGLIAGIISSTATGFLISQDFESGWRNVFFLSAAVNMFG 454
            ..:|..::.||::|.||..||.|:.|.|.|.|:|:....|.:........||.||:::..|..|.
  Fly   386 YYAGMKLSPLDMSPNYAGTLMAITNGIGAITGVITPYLVGVMTPNASLLEWRLVFWVAFGVLCFT 450

Human   455 LVFYLTFGQAELQ 467
            .|.|..:...|:|
  Fly   451 AVIYCIWASGEVQ 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC17A2	NP_001273052.1	2A0114euk	1..477	CDD:129972	146/468 (31%)
		MFS	81..461	CDD:119392	123/390 (32%)
dmGlut	NP_620115.2	2A0114euk	25..463	CDD:129972	137/443 (31%)
		MFS	77..458	CDD:119392	121/386 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148703
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D347586at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750