Protein Alignment DCAF7 and wap

DIOPT Version :10

• Sequence 1: NP_005819.3
• Gene: DCAF7 / 10238
• HGNCID: 30915
• Length: 342
• Species: Homo sapiens
• Sequence 2: NP_608461.1
• Gene: wap / 33131
• FlyBaseID: FBgn0266848
• Length: 343
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 293/342 - (85%)
• Similarity: 314/342 - (91%)
• Gaps: 2/342 - (0%)

Human     2 SLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFD 66
            |..|||||||||.|||.:|:||||||||||||||||||:||||||||::.|||::|||..::|||
  Fly     3 STAGKRKEIYKYLAPWPLYSMNWSVRPDKRFRLALGSFIEEYNNKVQIISLDEDTSEFSAKSTFD 67

Human    67 HPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEV 131
            |||||||:|||||:|||||||||||||||||||.||.:|||||:|||||||||||||||||||||
  Fly    68 HPYPTTKIMWIPDSKGVYPDLLATSGDYLRVWRAGEPDTRLECVLNNNKNSDFCAPLTSFDWNEV 132

Human   132 DPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVG 196
            ||.|:||||||||||||||||||...|| .|:|||||||||||||||||||||||||||||||||
  Fly   133 DPNLVGTSSIDTTCTIWGLETGQPHARV-YVAGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVG 196

Human   197 ADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVAR 261
            |||||||||||||||||||||||.|..||||.|||||||||||:|||..||:|||||||||||||
  Fly   197 ADGSVRMFDLRHLEHSTIIYEDPAHTALLRLAWNKQDPNYLATVAMDSCEVIILDVRVPCTPVAR 261

Human   262 LNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYT-AEGEINNVQWASTQ 325
            |:||||||||||||||||||||||.||||||||||||||||||||||||| ||||:|.:||.:||
  Fly   262 LSNHRACVNGIAWAPHSSCHICTAGDDHQALIWDIQQMPRAIEDPILAYTAAEGEVNQIQWGATQ 326

Human   326 PDWIAICYNNCLEILRV 342
            |||||||||...|||||
  Fly   327 PDWIAICYNKACEILRV 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCAF7	NP_005819.3	WD 1	6..52		38/45 (84%)
		WD40	<19..330	CDD:441893	269/311 (86%)
		WD 2	60..100		33/39 (85%)
		WD40 repeat	71..116	CDD:293791	38/44 (86%)
		WD 3	108..150		38/41 (93%)
		WD40 repeat	124..171	CDD:293791	38/46 (83%)
		WD 4	165..206		40/40 (100%)
		WD40 repeat	177..217	CDD:293791	39/39 (100%)
		WD 5	213..252		30/38 (79%)
		WD40 repeat	224..264	CDD:293791	34/39 (87%)
		WD 6	257..296		36/38 (95%)
		WD40 repeat	269..294	CDD:293791	23/24 (96%)
		WD 7	303..342		30/39 (77%)
wap	NP_608461.1	WD40	19..295	CDD:475233	239/276 (87%)
		WD40 repeat	75..117	CDD:293791	35/41 (85%)
		WD40 repeat	125..171	CDD:293791	38/46 (83%)
		WD40 repeat	177..217	CDD:293791	39/39 (100%)
		WD40 repeat	224..264	CDD:293791	34/39 (87%)
		WD40 repeat	269..294	CDD:293791	23/24 (96%)