DRSC/TRiP Functional Genomics Resources

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Protein Alignment HNRNPR and esf2

DIOPT Version :9

Sequence 1:NP_001095868.1 Gene:HNRNPR / 10236 HGNCID:5047 Length:636 Species:Homo sapiens
Sequence 2:NP_595758.1 Gene:esf2 / 2540503 PomBaseID:SPBC28E12.05 Length:334 Species:Schizosaccharomyces pombe


Alignment Length:332 Identity:63/332 - (18%)
Similarity:106/332 - (31%) Gaps:122/332 - (36%)


- Green bases have known domain annotations that are detailed below.


Human    57 YVDL-------DERAIDALREF-NEEGALSVLQQFKESDLSHVQNKSAFLCGVMKTYRQR---EK 110
            |||.       |||.:.|:|.. :.:..:.||:...||....::.:.|.|    ..:|:.   |.
pombe    16 YVDQDLSEDEEDERFLKAIRSSRSTKPVVDVLKVKSESSADELEERDAHL----DRFRRDSTFES 76

Human   111 QGSKVQESTKGP----DEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGVQPGIGTEVFVGK 171
            :.|..::.:.|.    ||...|........:|:....|||      ....|||       :::.:
pombe    77 ETSDHEDFSGGSENELDEETTKNANSIKKISLEEVEKQRK------AIKRSGV-------IYLSR 128

Human   172 IPRDLYEDELVPLFEKAGPIWDLRLMMDPLSGQNRGY--------------AFITFCGKEAAQEA 222
            ||..:..::|..:..:.|.|.  |:.:.|.|...|..              .:|.|..|..|:..
pombe   129 IPPYMAPNKLRQILSQYGKIG--RVYLTPESSAKRAQRLRNGGNKRVMYEEGWIEFESKRVAKSV 191

Human   223 VKLCDSYEIRPGK--------------------HLGVCISVAN---------------------- 245
            .:|.::.:|...|                    ||...|:..|                      
pombe   192 AELLNTNQIGGKKSSWYHDDIWNMKYLPKFKWHHLTEQIAAENAARESRLKVEIEQGRKQLKQYM 256

Human   246 ----NRLFVGSIPKNKTKE---NILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 303
                |...:..|.|.:::.   |:..||                  |::.|...       ||.|
pombe   257 RNVENAKMIEGIRKKRSERDTLNVSTEF------------------PEETKDLS-------EDTK 296

Human   304 SAAQARR 310
            .:.||||
pombe   297 PSKQARR 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HNRNPRNP_001095868.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
NURR_hnRNPR 27..110 CDD:410955 15/63 (24%)
hnRNP-R-Q 106..631 CDD:273732 49/275 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 415..459
Nuclear localization signal. /evidence=ECO:0000255 415..421
RNA-binding RGG-box 450..570
3 X 11 AA approximate repeats of D-D-Y-Y-G-Y-D-Y-H-D-Y 465..500
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 504..636
esf2NP_595758.1 RRM_ABT1_like 122..219 CDD:240709 18/105 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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