DRSC/TRiP Functional Genomics Resources

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Protein Alignment LRRC23 and CG14185

DIOPT Version :9

Sequence 1:NP_001128689.1 Gene:LRRC23 / 10233 HGNCID:19138 Length:343 Species:Homo sapiens
Sequence 2:NP_649175.1 Gene:CG14185 / 40197 FlyBaseID:FBgn0036936 Length:402 Species:Drosophila melanogaster


Alignment Length:226 Identity:54/226 - (23%)
Similarity:84/226 - (37%) Gaps:64/226 - (28%)


- Green bases have known domain annotations that are detailed below.


Human   145 QITDTEGISH-------------------PRLETLNLKGNSIHMVTGLDPEKLISLHTVELRG-- 188
            |.||.|.:..                   |||::|:|.|:.:..:..|. ..|:.|..:::..  
  Fly   115 QRTDLEAVEQVRLRVISYTVSLSRLSLFLPRLQSLDLSGSVLSSLRDLG-YGLLQLTRLDISNCG 178

Human   189 -NQLESTLGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLSGFSREMKSLQYLNL 252
             |..:.|.|  ||.::.|....||:::|:.|.:|     :|||                  .|..
  Fly   179 LNSFDGTSG--LPAIRVLIADGNMIQRVDPLAEL-----VHLR------------------VLKA 218

Human   253 RGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPYLERLD----------KEFY 307
            |.|.::.||.|:.|...|:|:.:.|..||......||......:|.|:.||          .|..
  Fly   219 RNNRISELGLLSFLGMCPQLQEVELQGNPVCRLPLYRSLLARSVPTLQLLDGRVLNGEPAPVEME 283

Human   308 EEEERAEADV------IRQRLKEEKEQEPEP 332
            |....|.:|:      ..||.......||.|
  Fly   284 EATSPASSDLESGSETTAQRPNTAPAPEPVP 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LRRC23NP_001128689.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..47
LRR 1 92..113
leucine-rich repeat 93..114 CDD:275380
LRR 2 114..134
leucine-rich repeat 115..135 CDD:275380
LRR 3 135..155 4/28 (14%)
leucine-rich repeat 136..156 CDD:275380 4/29 (14%)
LRR 4 156..177 6/20 (30%)
leucine-rich repeat 157..180 CDD:275380 6/22 (27%)
LRR 5 180..200 4/22 (18%)
leucine-rich repeat 181..201 CDD:275380 5/22 (23%)
LRR_8 200..255 CDD:290566 12/54 (22%)
LRR_4 200..241 CDD:289563 10/40 (25%)
LRR 6 201..222 5/20 (25%)
leucine-rich repeat 202..223 CDD:275380 6/20 (30%)
LRR_4 223..265 CDD:289563 9/41 (22%)
LRR 7 223..244 3/20 (15%)
leucine-rich repeat 224..246 CDD:275380 3/21 (14%)
LRR 8 246..267 6/20 (30%)
leucine-rich repeat 247..271 CDD:275380 7/23 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..343 5/15 (33%)
CG14185NP_649175.1 LRR_8 144..201 CDD:290566 16/59 (27%)
leucine-rich repeat 146..168 CDD:275380 6/22 (27%)
LRR_4 168..209 CDD:289563 11/42 (26%)
leucine-rich repeat 169..190 CDD:275380 5/22 (23%)
leucine-rich repeat 191..212 CDD:275380 6/25 (24%)
leucine-rich repeat 213..237 CDD:275380 9/41 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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