Protein Alignment PLIN3 and Lsd-2

DIOPT Version :10

• Sequence 1: NP_005808.3
• Gene: PLIN3 / 10226
• HGNCID: 16893
• Length: 434
• Species: Homo sapiens
• Sequence 2: NP_572996.1
• Gene: Lsd-2 / 32437
• FlyBaseID: FBgn0030608
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 301
• Identity: 62/301 - (20%)
• Similarity: 121/301 - (40%)
• Gaps: 42/301 - (13%)

Human     2 SADGAEADGSTQVTVEEPVQQPSV------VDRVASMPLISSTCDMVSAAYASTKESYPHIKTVC 60
            :.:|...:|:....|::|.....:      ::|:..:|::::..|.....|...|......:...
  Fly    10 TGNGTTGNGTAMNDVDQPKDAKDLLPHLESLERIIKLPVVNAAWDKSQDVYGKVKGKNRVFEWAL 74

Human    61 DAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELV 125
            .|||..|    ..||:.|.|.::||:..||...:...:|:||||...||::...:::....|
  Fly    75 TAAEDCV----TRAVTTAAPFVTKLDRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAK--- 132

Human   126 SSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVD 190
             |||.          |.|...| |.|...:.|.|......|.:.......|:.::.|.:.::|||
  Fly   133 -SKVI----------DVVQPHL-ERVVKFKAAGQQKAASLKDLAWQKANEVLATQYGSLAVNGVD 185

Human   191 TVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQS------------YFVR-LGSL 242
            |....:|...:.:.|..:::   :....|....|.||..:..::            :.|: :|.|
  Fly   186 TTTALAERLLEYYFPKCESD---VEEDNDDKQNAVVQNGKSSENDMPVPASEDPVLHTVQTVGRL 247

Human   243 SERLRQHAYEHSLGKLR-ATKQRAQEALLQLSQVLSLMETV 282
            |.::.:..|.:...::: ..|....:.|..|...|.|.:.:
  Fly   248 SNKISRRVYRNVSRQIKQVQKGNINDYLSSLIAALKLHQYI 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PLIN3	NP_005808.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		4/19 (21%)
		Perilipin	18..425	CDD:460784	59/285 (21%)
Lsd-2	NP_572996.1	Perilipin	40..>301	CDD:460784	58/271 (21%)