Protein Alignment TRIB1 and Trib1

DIOPT Version :10

• Sequence 1: NP_079471.1
• Gene: TRIB1 / 10221
• HGNCID: 16891
• Length: 372
• Species: Homo sapiens
• Sequence 2: NP_653132.1
• Gene: Trib1 / 211770
• MGIID: 2443397
• Length: 372
• Species: Mus musculus
• Alignment Length: 372
• Identity: 349/372 - (93%)
• Similarity: 358/372 - (96%)
• Gaps: 0/372 - (0%)

Human     1 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYLSPPGS 65
            |||||||.|:|||||||||.|||||.||.|||||||.|||.||||||||||||||||||||||||
Mouse     1 MRVGPVRFALSGASQPRGPGLLFPAARGTPAKRLLDTDDAGAVAAKCPRLSECSSPPDYLSPPGS 65

Human    66 PCSPQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQDK 130
            ||||||||:..|.||...|:|||||||||||||||||||||||||||||||||||.|||||||||
Mouse    66 PCSPQPPPSTQGTGGSCVSSPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKEFPIKHYQDK 130

Human   131 IRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAH 195
            |||||||||||||||||||:|||:|||||||||||||||||||||||||||||||||||||||||
Mouse   131 IRPYIQLPSHSNITGIVEVLLGESKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAH 195

Human   196 CHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNTTGTY 260
            ||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||||
Mouse   196 CHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIIKGEDDALSDKHGCPAYVSPEILNTTGTY 260

Human   261 SGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPSE 325
            ||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||
Mouse   261 SGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHVSPKARCLIRSLLRREPSE 325

Human   326 RLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC 372
            |||||:||||||||.||||||:|||||||||||||||||||||||||
Mouse   326 RLTAPQILLHPWFEYVLEPGYVDSEIGTSDQIVPEYQEDSDISSFFC 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIB1	NP_079471.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		18/21 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	52..86		26/33 (79%)
		PK_TRB1	97..338	CDD:270925	234/240 (98%)
		COP1-binding. /evidence=ECO:0000250|UniProtKB:Q8K4K4	355..360		4/4 (100%)
Trib1	NP_653132.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		21/24 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..85		28/35 (80%)
		PK_TRB1	97..338	CDD:270925	234/240 (98%)
		COP1-binding. /evidence=ECO:0000269|PubMed:24003916	355..360		4/4 (100%)