Protein Alignment CDK7 and Pk34A

DIOPT Version :9

• Sequence 1: NP_001790.1
• Gene: CDK7 / 1022
• HGNCID: 1778
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_609603.1
• Gene: Pk34A / 34705
• FlyBaseID: FBgn0028410
• Length: 392
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 108/342 - (31%)
• Similarity: 161/342 - (47%)
• Gaps: 44/342 - (12%)

Human    11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL-SHPNI 74
            |.|..|.:|.|.|..||:|....:.:|||:|:..  :..:...|       |.:::.:| .|.||
  Fly    43 RIEVKDLIGSGSFGRVYQAHVNESEEIVAVKQTL--YNPKLSQG-------EAEIMGQLKDHNNI 98

Human    75 IGLLD------AFGHKSNISLVFDFMETDLEVIIKDNSLVLTPS----HIKAYMLMTLQGLEYLH 129
            :.|:.      .|.....:.||.::|...|...|..:..||.|:    :::.......:||.|||
  Fly    99 VRLIMHSSVSLGFPSVDYVLLVMEYMPMTLLDYINYHLTVLQPAERLINVRILSYQMFRGLGYLH 163

Human   130 QHWILHRDLKPNNLLLD-ENGVLKLADFGLAKSF--GSPNRAYTHQVVTRWYRAPELLFGARMYG 191
            ...|.|||:||.|||:| :..||||:|||.||..  ..|:.:|   :.:|.||||||..|..:|.
  Fly   164 LLGISHRDVKPENLLIDNQKMVLKLSDFGSAKLLVPQEPSISY---ICSRLYRAPELFAGYELYS 225

Human   192 VGVDMWAVGCILAELLLRVP-FLPGDSDLDQLTRIFETLGTPTEEQWPDM---C--SLPDYVTFK 250
            ..||:|:.||:|||||...| |.....|..||..|...|||...|:.|::   |  ||....|..
  Fly   226 CAVDIWSAGCVLAELLKGYPLFSSHKHDRKQLRLIVNMLGTDGLERAPEILSKCGNSLHPRTTRP 290

Human   251 SFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQAL------KMKYFSNRPGPTP-GCQLP 308
            |:.    :.:.:|...||..|:...|::...|||:...|.      :::.......|.| |..||
  Fly   291 SWN----YLLNTAVPQDLCGLLNSCFIYEAAARISPMMACSHGSYDELRIMDAMALPMPNGNPLP 351

Human   309 RPNCPVETLKEQSNPAL 325
             |.....:|:..::|.|
  Fly   352 -PLFDFNSLEMGTDPKL 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK7	NP_001790.1	STKc_CDK7	11..308	CDD:270833	102/323 (32%)
Pk34A	NP_609603.1	STKc_GSK3	39..334	CDD:271039	99/306 (32%)
		S_TKc	45..328	CDD:214567	98/298 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910