Protein Alignment CDK7 and Cdk7

DIOPT Version :9

• Sequence 1: NP_001790.1
• Gene: CDK7 / 1022
• HGNCID: 1778
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_511044.1
• Gene: Cdk7 / 31441
• FlyBaseID: FBgn0263237
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 349
• Identity: 231/349 - (66%)
• Similarity: 278/349 - (79%)
• Gaps: 7/349 - (2%)

Human     1 MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKL 65
            |..:...:.:||.||.|||||||||||||||..||||||:||||.|.|.:|:||||||||||||:
  Fly     1 MLPNANDKTERYAKLSFLGEGQFATVYKARDTVTNQIVAVKKIKKGSREDARDGINRTALREIKI 65

Human    66 LQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQ 130
            ||||.|.|||||:|.||..||:|||||||:||||||||||.::||.::||||.:|||:||||||.
  Fly    66 LQELQHENIIGLVDVFGQLSNVSLVFDFMDTDLEVIIKDNKIILTQANIKAYAIMTLKGLEYLHL 130

Human   131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVD 195
            :|||||||||||||::.:|:||:.|||||||||||||.|||.|||||||:||||||||.||.|||
  Fly   131 NWILHRDLKPNNLLVNSDGILKIGDFGLAKSFGSPNRIYTHHVVTRWYRSPELLFGARQYGTGVD 195

Human   196 MWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHI 260
            |||||||||||:|||||:|||||||||||||.|||||||.:||.:..|.||:.|::|||.||.:|
  Fly   196 MWAVGCILAELMLRVPFMPGDSDLDQLTRIFSTLGTPTEAEWPHLSKLHDYLQFRNFPGTPLDNI 260

Human   261 FSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPAL 325
            |:|||:||:.|:|.||..||..|::..:||.|.||:|:|.||.|.:||.|:. :...||.:||..
  Fly   261 FTAAGNDLIHLMQRLFAMNPLRRVSCREALSMPYFANKPAPTVGPKLPMPSA-ILAAKEGANPQT 324

Human   326 -----AIKRKRTEALEQG-GLPKK 343
                 |:|||..|...:| ||.:|
  Fly   325 GDTKPALKRKLVETTVRGNGLAQK 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK7	NP_001790.1	STKc_CDK7	11..308	CDD:270833	214/296 (72%)
Cdk7	NP_511044.1	PTZ00024	6..308	CDD:240233	214/301 (71%)
		STKc_CDK7	11..308	CDD:270833	214/296 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143676
Domainoid	1	1.000	440	1.000	Domainoid score	I555
eggNOG	1	0.900	-	-		E1_KOG0659
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1363
Inparanoid	1	1.050	470	1.000	Inparanoid score	I1530
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1367115at2759
OrthoFinder	1	1.000	-	-		FOG0003675
OrthoInspector	1	1.000	-	-		oto88653
orthoMCL	1	0.900	-	-		OOG6_103547
Panther	1	1.100	-	-	LDO	PTHR24056
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R249
SonicParanoid	1	1.000	-	-		X2548
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790