Protein Alignment DHRS2 and CG12171

DIOPT Version :10

• Sequence 1: NP_878912.1
• Gene: DHRS2 / 10202
• HGNCID: 18349
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_649563.1
• Gene: CG12171 / 40690
• FlyBaseID: FBgn0037354
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 190
• Identity: 62/190 - (32%)
• Similarity: 103/190 - (54%)
• Gaps: 2/190 - (1%)

Human    36 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVA-GIVCHVGKAED 99
            ::|.:|||::||||...:..||:.|..:.|..|....::....::...|.:.| .:...:....|
  Fly     6 DKVIIVTGASSGIGAGTSVLLAKLGGLLTIVGRNLDKLNETAEQIVAAGGAPALQVAADINSESD 70

Human   100 REQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRR 164
            .:.:|:..|...|.:|.||.:||:..| ||...||.:.:|::::.||:|...|...:.|.:...:
  Fly    71 VQGIVSATLAKHGRIDVLVNNAGILEL-GSIENTSLEQFDRVMNTNVRSLYQLTHLVTPELIKTK 134

Human   165 GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSK 224
            |.::.|||:........:..|||||.|:...||.:|||||||.:|||.|.||:|.|:..:
  Fly   135 GNIVNVSSVNGIRSFPGVLAYNVSKAAVDQFTRCVALELAPKGVRVNSVNPGVIITELQR 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHRS2	NP_878912.1	Rossmann-fold NAD(P)(+)-binding proteins	27..>226	CDD:473865	62/190 (33%)
CG12171	NP_649563.1	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	62/190 (33%)