Protein Alignment DHRS2 and CG31549

DIOPT Version :10

• Sequence 1: NP_878912.1
• Gene: DHRS2 / 10202
• HGNCID: 18349
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_730972.2
• Gene: CG31549 / 40689
• FlyBaseID: FBgn0051549
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 195
• Identity: 66/195 - (33%)
• Similarity: 104/195 - (53%)
• Gaps: 12/195 - (6%)

Human    36 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAG------IVCHV 94
            ::|.:|||::||||.:.|..||:.|..:||..|.::.:     |...:.:..||      :...:
  Fly     6 DKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKL-----KETADNIVAAGGATPLELQADM 65

Human    95 GKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPY 159
            .|..:.:|:|...|...|.:|.||.:||:.. .||...||.:.:|::::.||:|...|.....|.
  Fly    66 TKEAEVQQIVGATLAKHGRIDVLVNNAGILE-TGSIEATSLEQFDRLMNTNVRSLYQLTMLATPE 129

Human   160 MENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSK 224
            :...:|.::.|||:........:..|||||.|:...|..:|||||||.:|||.|.||:|.||..|
  Fly   130 LVKTKGNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVNAVNPGVIVTDIHK 194

Human   225  224
              Fly   195  194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHRS2	NP_878912.1	Rossmann-fold NAD(P)(+)-binding proteins	27..>226	CDD:473865	66/195 (34%)
CG31549	NP_730972.2	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	66/195 (34%)