Protein Alignment DHRS2 and CG3699

DIOPT Version :10

• Sequence 1: NP_878912.1
• Gene: DHRS2 / 10202
• HGNCID: 18349
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_569875.2
• Gene: CG3699 / 31046
• FlyBaseID: FBgn0040349
• Length: 251
• Species: Drosophila melanogaster
• Alignment Length: 241
• Identity: 81/241 - (33%)
• Similarity: 127/241 - (52%)
• Gaps: 9/241 - (3%)

Human    34 LANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAE 98
            |:|:|.:|||::||||.|||:.|||:||.:.:..|...|::.....|:|....:  :|..|.|
  Fly     3 LSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEI--VVADVTK-- 63

Human    99 DREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENR 163
            |.:.:|.:.|...|.:|.||.:||:.. .|..:....:.:|.:|:.|::...||...:||::...
  Fly    64 DADAIVQQTLAKFGRIDVLVNNAGILG-KGGLIDLDIEEFDAVLNTNLRGVILLTKAVLPHLLKT 127

Human   164 RGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVVRI 228
            :|||:.|||.|...|......|.|||.||...|:.:|||:||:.:|||.|.||.:.|:..:  .|
  Fly   128 KGAVVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNPGFVVTNIHR--NI 190

Human   229 GFMGMSLSGRTSRNIIS--CRGLGSQRTVQESCPSCALQMPATSTG 272
            |.:....:|...|.|.|  ...:|....|.|:....|....:.:||
  Fly   191 GIVDEEYNGMLQRAINSHPMGRVGDVTEVAEAVAFLASSKASFTTG 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHRS2	NP_878912.1	Rossmann-fold NAD(P)(+)-binding proteins	27..>226	CDD:473865	69/191 (36%)
CG3699	NP_569875.2	Rossmann-fold NAD(P)(+)-binding proteins	3..248	CDD:473865	81/241 (34%)