Protein Alignment CDK5 and CG6800

DIOPT Version :9

• Sequence 1: NP_004926.1
• Gene: CDK5 / 1020
• HGNCID: 1774
• Length: 292
• Species: Homo sapiens
• Sequence 2: NP_650984.1
• Gene: CG6800 / 42562
• FlyBaseID: FBgn0038902
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 112/291 - (38%)
• Similarity: 163/291 - (56%)
• Gaps: 25/291 - (8%)

Human     3 KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLH 67
            :|:.|||||||.:|.||||.:.:.::.||:|:|.|.:....:..:.||||..|:..|.:.|:.:.
  Fly     8 RYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKFGNIALNTLREIKTLQLCKSEYILDII 72

Human    68 DVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNL 132
            |:......|:||.|:....|.....|....|..:.|:.|..|:.||:.:.|...::|||:||.||
  Fly    73 DIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGLMHRDIKPANL 137

Human   133 LINRNGELKLADFGLARAFGIP---VRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAE 194
            ||:....||:|||||||.: .|   .|.||.:|.|.|||.|::|||::.|.|.:|||:|||:.||
  Fly   138 LISDTDMLKIADFGLARLY-FPEDESRLYSPQVSTRWYRAPEILFGSQKYGTGVDMWAAGCVVAE 201

Human   195 LANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP--YP---------MYPATTSL 248
            :.. |.|||.|....:||..|.|.||:|...|||.:|.||||..  :|         ::|:.|..
  Fly   202 MLR-GVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLPDYSKIRFPNSVGIHWDNLFPSCTHA 265

Human   249 VNVVPKLNATGRDLLQNLLKCNPVQRISAEE 279
            |.:         :|:.||:..||..|:.|.|
  Fly   266 VEI---------NLVSNLVVYNPKNRLKASE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK5	NP_004926.1	STKc_CDK5	3..286	CDD:143344	112/291 (38%)
CG6800	NP_650984.1	STKc_CCRK	8..295	CDD:270826	112/291 (38%)
		S_TKc	9..288	CDD:214567	112/290 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910