Protein Alignment CDK5 and Cdk5

DIOPT Version :10

• Sequence 1: NP_004926.1
• Gene: CDK5 / 1020
• HGNCID: 1774
• Length: 292
• Species: Homo sapiens
• Sequence 2: NP_477080.1
• Gene: Cdk5 / 36727
• FlyBaseID: FBgn0013762
• Length: 294
• Species: Drosophila melanogaster
• Alignment Length: 288
• Identity: 228/288 - (79%)
• Similarity: 255/288 - (88%)
• Gaps: 0/288 - (0%)

Human     1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVR 65
            ||||:|:|||||||||||||.:||:|.|||||||||||:||||||||||||||||||||||||||
  Fly     1 MQKYDKMEKIGEGTYGTVFKGRNRDTMEIVALKRVRLDEDDEGVPSSALREICLLKELKHKNIVR 65

Human    66 LHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQ 130
            |.||||||||||||||.|||||||||||.||::|..:.:||:.|||:||.||||.||||||||||
  Fly    66 LIDVLHSDKKLTLVFEHCDQDLKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQ 130

Human   131 NLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAEL 195
            |||||:|||||||||||||||||||:|||||||||||||||||||||||:|||||||||||.|||
  Fly   131 NLLINKNGELKLADFGLARAFGIPVKCYSAEVVTLWYRPPDVLFGAKLYTTSIDMWSAGCILAEL 195

Human   196 ANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGR 260
            |:||||||||:||.|||.:|||:||||.|:.||.::.|.||...|.:||.||...:||:||:.||
  Fly   196 ADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHLSDYVALPSFPAITSWSQLVPRLNSKGR 260

Human   261 DLLQNLLKCNPVQRISAEEALQHPYFSD 288
            ||||.||.|.|.||||||.|:|||||:|
  Fly   261 DLLQKLLICRPNQRISAEAAMQHPYFTD 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK5	NP_004926.1	STKc_CDK5	3..286	CDD:143344	223/282 (79%)
Cdk5	NP_477080.1	STKc_CDK5	3..286	CDD:143344	223/282 (79%)