Protein Alignment CDK5 and CG7236

DIOPT Version :10

• Sequence 1: NP_004926.1
• Gene: CDK5 / 1020
• HGNCID: 1774
• Length: 292
• Species: Homo sapiens
• Sequence 2: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Alignment Length: 303
• Identity: 117/303 - (38%)
• Similarity: 170/303 - (56%)
• Gaps: 25/303 - (8%)

Human     1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVR 65
            |.:||||.::|||:||.|:|.::|||..:||:||....:||..:...|||||.|||.|||.|:|.
  Fly    47 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVS 111

Human    66 LHDVLHSDKKLTLVFEFCD----QDLKKYFDSCNGDLDPE-IVKSFLFQLLKGLGFCHSRNVLHR 125
            |.:|....::|.||||||:    .:|:::...|     || :.|...:|.|.|:.:||.:..|||
  Fly   112 LLEVFRRKRRLHLVFEFCELTVLHELERHPQGC-----PEHLTKQICYQTLLGVAYCHKQGCLHR 171

Human   126 DLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGC 190
            |:||:|:|:...|::||.|||.||... |...|:..|.|.|||.|::|.|...|.|.:|:|:.||
  Fly   172 DIKPENILLTAQGQVKLCDFGFARMLS-PGENYTDYVATRWYRAPELLVGDTQYGTPVDVWAIGC 235

Human   191 IFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY------PMYPATTSLV 249
            :||||.. |..|:||....|||..|.:.||    :..|...::.....|      |:.|....|.
  Fly   236 LFAELVR-GEALWPGRSDVDQLYLIRKTLG----DLLPRHIQIFGQNEYFKGITLPVPPTLEPLE 295

Human   250 NVVP---KLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF 289
            :.:|   :.|....|.|:..|..:|.:|.|.|:..:|.||.|:
  Fly   296 DKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYFDDY 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK5	NP_004926.1	STKc_CDK5	3..286	CDD:143344	113/296 (38%)
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	113/297 (38%)