Protein Alignment MPHOSPH10 and CG13097

DIOPT Version :10

• Sequence 1: NP_005782.1
• Gene: MPHOSPH10 / 10199
• HGNCID: 7213
• Length: 681
• Species: Homo sapiens
• Sequence 2: NP_609237.1
• Gene: CG13097 / 34184
• FlyBaseID: FBgn0032051
• Length: 662
• Species: Drosophila melanogaster
• Alignment Length: 728
• Identity: 270/728 - (37%)
• Similarity: 360/728 - (49%)
• Gaps: 157/728 - (21%)

Human    22 TGRPECFLTIQEGLASKFTSLTKVLYDFNKILENGRIHGSPLQKLVIENFDDEQIWQQLELQNEP 86
            |..||.||..|....:....|.:..|..: |.|:.......|.:||:|..|:||||||||::||.
  Fly    24 TKNPERFLQPQPEQVNAIEQLIQQTYAVS-ISEDVANKKELLPELVLEQMDEEQIWQQLEIRNEL 87

Human    87 ILQYFQNAVSETINDEDISLLPESEEQEREEDGSEIEADDK----EDLEDLEEEEVSDMGNDDPE 147
            :   ||..:.:|..   ::.:.|.......:||.|||.:|:    ||..|.|::|.||
  Fly    88 V---FQQVLEQTAR---LTAMREQHLGIELDDGEEIEEEDEVIQAEDSGDEEQDEESD------- 139

Human   148 MGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEA 212
                              |||||..|.      :|::......:.|....|:|||.||||.||..
  Fly   140 ------------------FSDEDGGLQ------KQKTAPPKDKRNKRLRNSVVDDTFFKLEEMNE 180

Human   213 YLE----------NIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYK 267
            :||          |.:|..|:.||.|...||....|| :.|::||               |:.|.
  Fly   181 FLEQEDAKEMRRLNSKKRVEQADDIDHFAEDFGLGED-EEDDEEG---------------NVNYA 229

Human   268 DFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAE--------------ELSISETDEDDDLQEN 318
            ||||   .:|::|. |..:::..|:.|...|.|:|              :...||.||.||..||
  Fly   230 DFFD---MNEELTE-HSKKINKGKQKDFFNENESENENEPDEDANPKEGDSDQSEGDEGDDEPEN 290

Human   319 EDNKQHKESLKRVTFALPDDAETE-DTGVLNVK--------KNSDEVK-------------SSFE 361
            :.:              ||:|.:| |......|        .:||..|             ||.|
  Fly   291 DQD--------------PDEAASEIDESEFVAKSGIEPASDSDSDSEKEEEEPQPTEPPSQSSNE 341

Human   362 KRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEETTLQLE 426
            .|:.::.::|...|..:|.:|||||:|||.|..||:||||||.|.||...|....||||....:|
  Fly   342 MREARLFQRIRDYEDIVLGEKPWQLKGEVKAANRPQNSLLEEILDFDSTTRPTAPITEEDNRSIE 406

Human   427 DIIKQRIRDQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEY----IKLNQQKTAE 487
            |||||||||:|||||.|..:|.....||:|:|.||.||||.||::|||.:|    .||:..:.|:
  Fly   407 DIIKQRIRDKAWDDVERTVRPVNTPQEYRKQLVLDQEKSKQSLSQIYEAQYQREMEKLDPNRDAD 471

Human   488 E----ENPEHVEIQKMMDSLFLKLDALSNFHFIPKPPVPEIKVVSNLPAITMEEVAPVSVSDAAL 548
            :    |..||.||::.|.||||||||||||||.|||..||||:|:|.||:.||||||::||||.|
  Fly   472 DKTGPEPKEHQEIKRAMRSLFLKLDALSNFHFTPKPVAPEIKIVTNTPAVHMEEVAPLAVSDAKL 536

Human   549 LAPEEIKEKNKAGDI-KTAAEKTATDKKRERRKKKYQKRMKIKEKEKRRKLLEKSSVDQAGKYSK 612
            |||||:....|...: ||  |:..|||.||||||| ||:..|....::|:|       |..|..|
  Fly   537 LAPEEVFRGPKHAPLGKT--ERDRTDKNRERRKKK-QKQRAIHSALEQREL-------QRAKEGK 591

Human   613 TVASEK-----LKQLTKTGKASFIKDEGKDK-ALKSSQAFFSKLQDQVKMQINDAKKTEKKKKKR 671
            ....::     ||.:||......|.....|: |||||:|||.||||       .|..|..||:.:
  Fly   592 APTKKEADAKLLKTITKNRNVQKINASSNDQGALKSSKAFFHKLQD-------TAAATASKKRPK 649

Human   672 QDIS---VHKLKL 681
            :|.:   ..||||
  Fly   650 KDTAKADAKKLKL 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MPHOSPH10	NP_005782.1	Mpp10	25..573	CDD:461128	224/606 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	105..202		24/100 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..364		47/183 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	558..606		19/48 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	660..681		7/23 (30%)
CG13097	NP_609237.1	Mpp10	27..560	CDD:461128	224/606 (37%)
		RNB	<520..630	CDD:476861	50/119 (42%)