Protein Alignment RNF41 and Traf4

DIOPT Version :10

• Sequence 1: NP_005776.1
• Gene: RNF41 / 10193
• HGNCID: 18401
• Length: 317
• Species: Homo sapiens
• Sequence 2: NP_477416.1
• Gene: Traf4 / 33638
• FlyBaseID: FBgn0026319
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 236
• Identity: 52/236 - (22%)
• Similarity: 77/236 - (32%)
• Gaps: 88/236 - (37%)

Human    18 CPIC----SGV-LEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHLRPVPRIMRNML- 76
            |..|    ||. |||...:...|..:|.|...|                        ||:|..:
  Fly   164 CEFCQSEFSGAGLEEHNGSCGQEPVYCEAKCGQ------------------------RILRGRMT 204

Human    77 ---SKLQIACDNAVFGCSAVVR---LDNLMSHLSDCEHNPKRPVTCEQGCGL-EMPKDELPNHNC 134
               ||   .|...:..|:...|   .|.|..|.:.|   |:.|:.|.|.|.. .:|:.||.
  Fly   205 LHKSK---DCAKRLRRCAHCQREFSADTLPLHAAQC---PRAPLACPQRCDAGPIPRGELE---- 259

Human   135 IKHLRSVVQQ-----------------QQTRIAELEKTSAEHKHQL----AEQKRDIQLLKAYMR 178
             .|||...|.                 :|...|.||..:|.|...:    :.|.:.||:||:.:.
  Fly   260 -AHLRDECQSLAVSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMVALSSRQGQQIQMLKSAVS 323

Human   179 AIRSVNPNLQNLEETIEYNEILEWVNSLQPARVTRWGGMIS 219
            .:            :|.|...|.|       ::|.|...::
  Fly   324 KL------------SINYTGTLLW-------KITDWSAKMA 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF41	NP_005776.1	mRING-HC-C3HC3D_Nrdp1	15..57	CDD:438296	11/43 (26%)
		USP8_interact	137..315	CDD:430333	21/104 (20%)
Traf4	NP_477416.1	PLN03086	<109..206	CDD:178635	14/65 (22%)
		zf-TRAF	233..292	CDD:280357	15/66 (23%)
		MATH_TRAF4	331..479	CDD:239750	4/22 (18%)