DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment amfrb and syvn1

DIOPT Version :9

Sequence 1:	XP_005169066.1	Gene:	amfrb / 101884807	ZFINID:	ZDB-GENE-130530-643	Length:	459	Species:	Danio rerio
Sequence 2:	XP_012816157.1	Gene:	syvn1 / 100327246	XenbaseID:	XB-GENE-1005361	Length:	608	Species:	Xenopus tropicalis

Alignment Length:	380	Identity:	107/380 - (28%)
Similarity:	178/380 - (46%)	Gaps:	78/380 - (20%)

- Green bases have known domain annotations that are detailed below.

Zfish    59 ELYSTGLWCHTTGSLCMWVLVNTLCCFLLLMGKCIQLVVFGDLRINEKQNLKDKTWNFLFNKLIF 123
            :.|.|.::. |..|..|.||.......:.|:||.:..|.||.||..|.::|.:::| :...:...
Frog    27 QFYPTVVYL-TKSSPSMAVLYIQAFVLVFLLGKFMGKVFFGQLRAAEMEHLLERSW-YAVTETCL 89

Zfish   124 LFGVL-NVRTEREMAMWCLCFSALLFLQLLAQLCKDRFEFLSSSPSSTALGSHMHLLLVLMCL-- 185
            .|.|. :..:.|.:|:    |:.||||:....|.:||.:|:..||:.:.| .|..:|.:::.|
Frog    90 AFTVFRDDFSPRFVAL----FTLLLFLKCFHWLAEDRVDFMERSPNISWL-FHFRILALMLLLGV 149

Zfish   186 ----FVSSGGLTII----CVLLGFSFGMHTLSFMAVECLMVSVYVNHSILRYAIHLYDLMCDSSW 242
                |||....:::    .|.|.|.|     .:..:..::::|::     :|.:|..||..::.|
Frog   150 LDAFFVSHAYHSLVTRGASVQLVFGF-----EYAILMTMILTVFI-----KYVLHSVDLQSENPW 204

Zfish   243 EGKEVFIYYTDFVMEMGILLLDMMHHINMLLYGNVWFSVADLFILTHIR----FLAKEMQRKLFQ 303
            :.|.|::.||:.          :...|.:|||      :|.:.|:..:.    |..:.|...:.|
Frog   205 DNKAVYMLYTEL----------LTGFIKVLLY------MAFMTIMVKVHTFPLFAIRPMYLAMRQ 253

Zfish   304 HKNYMHIYDV---------MDTRFSMATMEELASRDDRCVICWEKMYT-AYKLPCGHLFHKSCLR 358
            .|.  .:.|.         |:|.:..||.|||.:.|:.|:||.|:|.| |.:|||.|:||.||||
Frog   254 FKK--AVTDAIMSRRAIRNMNTLYPDATTEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLR 316

Zfish   359 SWLEQNMSCPTCRMSVNMSGGHTGNEQEGALFSLGATDVPSRPPTRYHSQLFHFN 413
            ||.::..:||||||.|                 |.|: :|::|.|....|..|.|
Frog   317 SWFQRQQTCPTCRMDV-----------------LRAS-LPTQPQTPADQQNQHQN 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
amfrb	XP_005169066.1	HRD1	77..>403	CDD:227568	98/350 (28%)
amfrb	XP_005169066.1	zf-RING_2	331..371	CDD:290367	22/40 (55%)
syvn1	XP_012816157.1	HRD1	25..>344	CDD:227568	103/369 (28%)
syvn1	XP_012816157.1	PRK14950	<468..>575	CDD:237864
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56438
OrthoDB	1	1.010	-	-		D271732at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.930