DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fat4 and ds

DIOPT Version :9

Sequence 1:	XP_021336971.1	Gene:	fat4 / 101882648	-ID:	-	Length:	4918	Species:	Danio rerio
Sequence 2:	NP_001285551.1	Gene:	ds / 33245	FlyBaseID:	FBgn0284247	Length:	3556	Species:	Drosophila melanogaster

Alignment Length:	3917	Identity:	1080/3917 - (27%)
Similarity:	1687/3917 - (43%)	Gaps:	842/3917 - (21%)

- Green bases have known domain annotations that are detailed below.

Zfish     7 STHLVLLVFWTL--SRCSVSSQVRQ-EFEVLE----EQPVGTYVGT---IETKPAFTYRFSEQHK 61
            |:.|:||....|  |:.:...|.|: :.||.|    :..:| |:|.   |::.|.:........:
  Fly    57 SSLLILLAIVLLGSSQAASHDQERERKLEVFEGVAVDYQIG-YIGDFGGIDSGPPYIIVAEAGVE 120

Zfish    62 L-FSINATTGVIYTSSVIDREVLPGNIINVVVLSSQPTYPTEVRIVVLDINDNAPVFPDASIVVS 125
            . .:|:..||.|.|...:|||......:..:.||.:   ...|.:.|.|.|||||.||..|:.:.
  Fly   121 TDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSGR---NIRVLVTVKDENDNAPTFPQTSMHIE 182

Zfish   126 FKEDASSGRQVILDTATDADIGSNGVDHTTYRIISGNDQRKFRLDITVNPSGEGAFLHLVSTGGL 190
            |.|:.....:..|..|.|.|:.......  |.|:|||....|||.......|. .:|.|..:|.|
  Fly   183 FPENTPREVKRTLLPARDLDLEPYNTQR--YNIVSGNVNDAFRLSSHRERDGV-LYLDLQISGFL 244

Zfish   191 DRETTPFYQLLIQVEDKGEPKKFGYLQVNVTIQDINDNPPSFDHEQYQTSVFEDAAVGSSVLQIA 255
            ||||||.|.|||:..|.|.|...|::.||:||||:|||.|.|:..:|..:|.|:|.||:||||:.
  Fly   245 DRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVY 309

Zfish   256 ASDLDEGANAEITYLL-----DEGTPFQIDPKAGTVVIKEGLDYETKREYSLTIHAVDNGVPSLY 315
            |||.|...|..:.|.:     |:...|:|||:.|.:.|.:.||:|||..:.|.:.|.|:|...|.
  Fly   310 ASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLE 374

Zfish   316 TRTEATVKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSTANGNISVSIL 380
            |....::::.|||||.|.:.. .|.:......:.|:||.|..||.::|.|.||.|...|::|::.
  Fly   375 TTAFVSIRVTDVNDNQPTINV-IFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLN 438

Zfish   381 GGNEQRHFDVHSSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPLARSSFASLVIFVNDIND 445
            ||:  .||.: ::...::.|:.|...||||.:|:|.|:|..:|.|.|...:| .|:.:.:.|:||
  Fly   439 GGD--GHFAL-TTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHAS-KSIFLRITDVND 499

Zfish   446 HPPIFQEAVYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVS--GNSLGWFAISENSGLVT 508
            :||.|::.:|..::.|....|:.:..|.|.|.|.|.|:.|.|||..  .....||.|...:||:|
  Fly   500 NPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLIT 564

Zfish   509 SAAELNRETASEIVLNISAKDQGLQPKISYTKLIVNITDVNDQVPTFTQNTYHVSITEHSPAGSE 573
            :.:.::.||.....|.:.|:|.|:.|..|...::|.|.||||..|.|.|:.|:||:.|:.|.|..
  Fly   565 TRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRC 629

Zfish   574 LVVLSATDSDLGPNGTIRFSFDSETPVSDQNKFRLDSTSGRLSTSTELDREEESSYLLYIRATDS 638
            ::.:||:|.|.|.|..:.::...  ......:|.:.|.||.:..:.|||.|..|||...:.|||.
  Fly   630 ILKVSASDPDCGVNAMVNYTIGE--GFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDR 692

Zfish   639 GAPPLHSVCKVNITLKDVNDNSPVFYPMQYFANIKE-----NEPSGSSVTTVTASDPDLGRNGTV 698
            |.  |.:...:.:.|.|||||.|||||.:|..:::|     ::.|.:.:..|.|:|||.|..|.|
  Fly   693 GG--LSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQV 755

Zfish   699 KYAITAG-DSSKFHISSTSGKVTTL--VALDREEKTAYQLQVTATDGGGLRSHTPAIVTVTVVDT 760
            .|.|.|| ::..|.|..::|::..:  ..|....:..:.|.::|||||.|||:..|:|.::::|.
  Fly   756 SYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDA 820

Zfish   761 QDNPLVFGQKDYSFVMFENVPVGTIIGTVSATTVDL--HTNITYLIASGDQRSLFGIK--AGQIT 821
            ...|.:|.:..|::.:.|::|.||::|:|.|.:.|:  .:.:.|.|.|||....|.|:  :|.|.
  Fly   821 MQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIR 885

Zfish   822 ALGLIDREEQAFYQLRVIARAGE--VTGETLVNITVKDLNDNAPNFMHSVEHVSAVENWATGHHI 884
            ....:|.|.::...|.:.|..||  |.|.|.|||.|:|:|||||.|..|:..:|..|:...|..:
  Fly   886 IAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPL 950

Zfish   885 FQAKASDPDEATNGMIVYSL-KQNPKGLFHIHEKHGLISLTGPLEVTTSS-YQLEVVASDLGVPQ 947
            :.|.|.|.|..::|.:.||| |::.||||.|..:.|.:.|:..|:..:|. :.|.|.|:|.|||.
  Fly   951 YAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPS 1015

Zfish   948 RTSSLFLTISVYDVNDNAPVFDQLSYEVTILESEPVNSRFFRVEATDKDSGVNGEIVYDIISGNT 1012
            .:::|.:.:.|.|||||.|||::..|.|.:.||..:|::..:|.|:|.|:|.|..|.|.|:....
  Fly  1016 LSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGV 1080

Zfish  1013 RDV------------FGIFPD-GQLYIKADLDREVQDRYSLLVVAKDRAVESLSASVNVSILLDD 1064
            .:|            |||||: |.:|::|.||||.:|||.|.|:|.|....:..|...|.:.:.|
  Fly  1081 DNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLD 1145

Zfish  1065 INDNRPLFNSTNYVFHFEEEQERGALVGRVFAEDKDFGPNSEVRYSFETPQSNFELNAITGVLTS 1129
            .|||.|.|..:.|.|..||...||::||.|.|.|.|.|.|:.:|||.....|:|:::.:||.:::
  Fly  1146 ANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEIST 1210

Zfish  1130 TLQLDRESLMRQRGAAVFSFTVLSSDQGLPKPLKDQAKVQVYIQDINDNPPKFT---KDIYQASI 1191
            ...||||  :|:    ::...|.:.|||.| ....:..|::::.|:|||.|:..   :|:  .|:
  Fly  1211 REPLDRE--LRE----LYDLVVEARDQGTP-VRSARVPVRIHVSDVNDNAPEIADPQEDV--VSV 1266

Zfish  1192 AESAQNMTQLLRVSASDVDENKNGLVHYDITEGNEEK---QFSIDSNSGQVTLVGKLDYETTPSY 1253
            .|.....|:::||.|.|.|..:|..:.|.|.:|.:..   .||||..||.:.....||:|....|
  Fly  1267 REEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIY 1331

Zfish  1254 SLKIIAEDSGSVPLSSTCVLSISVLDDNDNSPSFPKSTLSVDVLENMRIGELVASVTATD----- 1313
            .|.:.|.|.|:.|..:..:|.:.|||.|||.|:|..|:|...|.|:..:|.:|.|::..:
  Fly  1332 RLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADV 1396

Zfish  1314 -----SDSGSNADITYSISATNN---HGTFSISPNTGSIFLVKKLDYETQSLYKLNVTAKD---S 1367
                 .:|..:..:||:::....   ...|.|..::|::.:.:.||.|.||.::|.:.|.|   |
  Fly  1397 VRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTAS 1461

Zfish  1368 GRPSRSSSIPVIIHVRDFNDNPPVFTPGDIFKSIPENLPISTSVMSITAHDTDADINGLLEYSIA 1432
            ..| :||:|.|.|.|.|.|||.|.: |.|     |.:|.:|
  Fly  1462 NNP-QSSAITVKIEVADVNDNAPEW-PQD-----PIDLQVS------------------------ 1495

Zfish  1433 LQTPRGGHFRIDSVSGVIYTNKDIDREFSNLFELTIKATDQAVPAEFRRFALKNVTIWVTDQNDN 1497
                                                    :|.|
  Fly  1496 ----------------------------------------EATP--------------------- 1499

Zfish  1498 IPTFISQNALVAESNIVIGSILTTVLAFDPDEGANGEVEYELVRGDSDTFIMDRYSGDIRLASQL 1562
                             :|:|:....|.|.|.|.||:::|.|:|
  Fly  1500 -----------------VGTIIHNFTATDADTGTNGDLQYRLIR--------------------- 1526

Zfish  1563 IPSKLIYSLMVSATDHGTDRKSSRTELTIILQGTDGPVFSQPKYITILKEGQPAGTNVISLDASS 1627
                                                       |...|.|.|
  Fly  1527 -------------------------------------------YFPQLNESQ------------- 1535

Zfish  1628 PRGAGTKVEYFIVSVRSGGKAAGRLFTIGRHSGVIQTAAELDREQGSDLYLLDVYAIETDAKQPR 1692
                                                       ||...|
  Fly  1536 -------------------------------------------EQAMSL---------------- 1541

Zfish  1693 TQHAEGANALVTYAIISGADDSFRIDPESGELSATRRLDRERRSKYSLLVRADDGQQSSD----- 1752
                                  ||:|..:|.||....||.|...:|.|:|:|.|  |||:
  Fly  1542 ----------------------FRMDSLTGALSLQAPLDFEAVQEYLLIVQALD--QSSNVTERL 1582

Zfish  1753 ---IWVNITVSDINDHTPTF------SRSVYSFDIPEDMSPGSIVAAILASDGDSGVNGEITYSV 1808
               :.|.:.:.|.|||.|.|      .....|..|.:....|.:||.|:|.|.|||.||::||.:
  Fly  1583 QTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEI 1647

Zfish  1809 EEDDEDSTFLLNPITGVFNVTRAL-----DFETQPFFILTVRAADGG---GRSSSVRVYFNLLDV 1865
            ...:.:..|.:|..||:..:.::|     |.|....|.|.:.|.|.|   .:.||:.::..:...
  Fly  1648 TGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGS 1712

Zfish  1866 NDHPPLFNSSVYTTSILESLSAGASVLTVSAADRDHGPNADLHYSIASGDPQSQFSIT-NTGVLH 1929
            :::||.|..:||..:|||::.:|:.||.|:|.......||:|.|.|.:|.....|.:. ..|::.
  Fly  1713 HNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIIT 1777

Zfish  1930 TTKTLDRETQSFYNLVITVNDLALPPSTRFTSTAQISIILLDVNDCAPVFTSPRTAYIQENTPVD 1994
            |....|||:|:.|.|.:.|.| |...||..:|..:
  Fly  1778 TRGQFDRESQASYVLPVYVRD-ANRQSTLSSSAVR------------------------------ 1811

Zfish  1995 MRVFTAQASDADSGPNSYVEYSLSGAFGSKFGIGMIDGGVTLLGELDREEMENYTLTIVATDKGD 2059
                 .|.|....|..|.         |..|.                          |||
  Fly  1812 -----KQRSSDSIGDTSN---------GQHFD--------------------------VAT---- 1832

Zfish  2060 PPLSSSMEVIMMVLDVNDNTPSFSQ-NIYDIEIQENTLTGTDILQVFASDADEGTNGQIRFSITG 2123
                    :.:.|.|||||:|.|.. :.|.:.:.||:..|. |..|.|||.|||.|..:.:||||
  Fly  1833 --------IYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDEGPNADLIYSITG 1888

Zfish  2124 GNLNSDFRMDSVTGVISVAKLLDRESRSSYSLQVQAADRGSSPRVDRATVNIVLLDVNDCAPVFE 2188
            |||.:.|.:||.:|.:| |:.||||..|.|:||:||:|||.
  Fly  1889 GNLGNKFSIDSSSGELS-ARPLDREQHSRYTLQIQASDRGQ------------------------ 1928

Zfish  2189 LSPYTISVQENLGNLPKNILQVVARDDDLGTNGQISYSLSSGNDAGAFSLSASGQLNLIHTLDRE 2253
                           ||                                 |..|..|
  Fly  1929 ---------------PK---------------------------------SRQGHCN-------- 1937

Zfish  2254 TQDTHTLIITAHDAGLPSLSGSGTVTVLVGDVNDNIPSFSSMSFHTTIPEDAPTGTDVLLLNSSD 2318
                                    :|:.|.|.|||.|.|....:..::.||||.||.|:.:::.|
  Fly  1938 ------------------------ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVD 1978

Zfish  2319 SDVGLNGVISYSLSG-GDGQFSINPSTGLIITSSLLDRETRASYQLLVVASDGGQPTPLSSSATV 2382
            :|:|:|..:.|||:. ...||:|:..:|||.|...||||.:|||..:|:|:|||:....|::..|
  Fly  1979 ADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPV 2043

Zfish  2383 SVVVADINDNPPRFHHHPYVTHIPASTSTGSLVFAVTVTDEDSGSNSQLHYSLTGRN---SEKFK 2444
            .:.|.|||||.|.|..:||:..:||....|..:..|...|.|.|:|:::.|||...|   |.||:
  Fly  2044 QINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFR 2108

Zfish  2445 IDPIRGAITASEKLTGSSEVTFTVHV--KDGGTNPKTDSTTVTVRFVTGGDFPH----IKLKDKA 2503
            |:|..||::||:.|...|.....:.|  :|.|..|::....:.:..   |:.|.    ::.:::.
  Fly  2109 INPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLI---GEAPQGTPVLRFQNET 2170

Zfish  2504 F--TFPENQPTNTIVTKVTG--SSPRAGPLSYYIASGNLDNAFHIDQLSGELSIRKP--LDY--- 2559
            :  ...||.|:.|.:.:|..  |..|...:.:...:||.|....:|.||||:.:.||  |||
  Fly  2171 YRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRF 2235

Zfish  2560 -----------------ENIEK--------------------YVLW----------IEARDQGFP 2577
                             |.|::                    :.|.          :.||....|
  Fly  2236 STPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAP 2300

Zfish  2578 PYSAYEKVEIAVLDVNDNHPVFEQEPFHAEILE-NLSPQRVLVVSALDQDSGPNGQLEYAIIDGN 2641
            ..::|.::.|.:.|.|||.|.|.|:.|.|.:.| |.....|..|.|.|.|:|.|.:|.|.|:|||
  Fly  2301 FLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGN 2365

Zfish  2642 KENSFNINRA-TGEIRTTRPLDREKVAQYSLRVKATDRGMPPKSTAVKVLISVLDVNDNAPRFSK 2705
            .:|:|.|..| :|.:||...||||....|.|::.|||.|:|..:....:.:.::|||||.|.|..
  Fly  2366 HDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPP 2430

Zfish  2706 IFSATVPENAPVGFTVTRVTTTDEDA--------GANAISRYSITDASLPFIIHPSTGDITISRP 2762
            ....||.|...:|..:|.::..|.|.        ||.  |...|.:.|: |.:...:|.:.:.|.
  Fly  2431 NNLVTVSEATELGAVITSISANDVDTYPALTYRLGAE--STVDIENMSI-FALDRYSGKLVLKRR 2492

Zfish  2763 LNREDTDHYIAKVSAHDSGWTVSTDVTIFVTDINDNAPRF---SKPSYYLDYPELTEIGSIVT-- 2822
            |:.|....|...|.|.|:.....|.:|:.|.|.|||||.|   ..|:|:...|.::||...::
  Fly  2493 LDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVD 2557

Zfish  2823 ----QVSATDPD-EGFNGKIFYFIRSQTEYFRINSSSGEIFIKQQLRYQ---NSSGHNNINVNRH 2879
                .|:|||.| ||.|.|:.|.|....|.|.::.|:|.:.:... |.|   :|||...:.
  Fly  2558 FDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMS-RLQPAVSSSGDYFVR---- 2617

Zfish  2880 SFIVTASDRGIKPLMSETTVMINVVDSNDNPPTFESPSYFTPVTKSVKVGTRLLKVTAYDKKDFG 2944
               :.|.|.|...|.|.|.:.:...|:......|....|...::::..:|:.:|:: ..|..|..
  Fly  2618 ---IIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQL-GQDALDQS 2678

Zfish  2945 LNSEIEYAISGGNSSNKFRLDKQTGSVTVASSLAADTNKVYLLEITASDKGNPPL------SDRT 3003
            |      ||..||..:.|.| .|:.::.:...|..:.|.:|.|.:..|....|||      |...
  Fly  2679 L------AIIAGNEESAFEL-LQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGI 2736

Zfish  3004 TVKIAVTEENHHTPEFSQN-QVTVTVSEALTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDG 3067
            :|.|.:.:.|.:.|.|.:: :....:||...:..:|..|.|.|.|::...|..:.|:|:||||:.
  Fly  2737 SVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEH 2801

Zfish  3068 LFSVHSQTGVLSLAKTLDYETKQK-HELRVSATDGGWIAK-TSYVTVNIQVTDVNDNPPVFDPVE 3130
            :|::...||||.:...|||::..| :||.:.|.|...... .|.....:::.|.|||.|.|...|
  Fly  2802 MFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTE 2866

Zfish  3131 YFPVVQENVPSGTTVVKMNATDKDSGSNALMAYVIQSSDSD-----LFIIDPNTGIITTQGFLDY 3190
            |...:.||.|.|::|.:.:|:|.|.|....:.|.|..:.||     :|.:|..:|::|:....||
  Fly  2867 YVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDY 2931

Zfish  3191 EAKQVYHLTVKAFNVPDEERCSFAYVNIQLKGANEYVPRFVSKQYYFEI--SEAAPKGTVVGEVF 3253
            |.:|.|.:.:.|.:: ..::.|.| |.::::..:|:.|:|..:.|.|.:  :.|.|:|.|||:|.
  Fly  2932 EQRQRYDMELLASDM-GGKKASVA-VRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVT 2994

Zfish  3254 ASDRDLGEDG-VVYYLIFGRSRKRGFSINKKTGQIYVSGSLDREKEEKISLKVLAKNAGSI--RG 3315
            |:|.|.|.|| |||.|....|.   |.:|:.:|.:.:          |..||:.....|::  .|
  Fly  2995 ATDSDSGPDGRVVYQLSAPHSH---FKVNRSSGAVLI----------KRKLKLDGDGDGNLYMDG 3046

Zfish  3316 ADIDEVLVNITVLDANDPPVFTQELYDVQVNEGLSPGGLVTFVSAEDSDSVPSWS-----RFTYA 3375
            .||..|   |:........:.:..:.::.::....||..:.......|.|:..|:     .|...
  Fly  3047 RDISLV---ISASSGRHNSLSSMAVVEIALDPLAHPGTNLASAGGSSSGSIGDWAIGLLVAFLLV 3108

Zfish  3376 IAA------------NHERNTFTINPQTGQVSVA---SELDR---ETVPVYNLTILAVDSGSPAA 3422
            :.|            ...||....:..|....|.   |.:|.   :|:|:..    ::..|:..|
  Fly  3109 LCAAAGIFLFIHMRSRKPRNAVKPHLATDNAGVGNTNSYVDPSAFDTIPIRG----SISGGAAGA 3169

Zfish  3423 TGSAILIVTLEDI----NDNGPTLVTTYGEVMENQRAGTPVMTLSSR--------DPDLAP-NQG 3474
            ..........::|    ...|.:...|..|:..::::|:     |.|        |.::.. |:|
  Fly  3170 ASGQFAPPKYDEIPPFGAHAGSSGAATTSELSGSEQSGS-----SGRGSAEDDGEDEEIRMINEG 3229

Zfish  3475 PFTYSLVSTGAASSYFTISPTGELTTSREVDREQI-----------------SDFYLSVLIKDSG 3522
            |..:.....||.|....||......|...:.|..|                 |...:.:...|..
  Fly  3230 PLHHRNGGAGAGSDDGRISDISVQNTQEYLARLGIVDHDPSGAGGGASSMAGSSHPMHLYHDDDA 3294

Zfish  3523 IPQMSSTGTVHIKVNDQNDNPSESRS-----------------------------------VEIY 3552
            ..:...|..::.|:||.....||..|                                   |.:.
  Fly  3295 TARSDITNLIYAKLNDVTGAGSEIGSSADDAGTTAGSIGTIGTAITHGHGVMSSYGEVPVPVPVV 3359

Zfish  3553 VHYFGNMFPGGSLGVVKPQDPDIQDTFQCSLT-------PPAALLFSIPTGTCDLISNSRSTDGT 3610
            |   |....||||..:...:.::..::.....       .|.|.:||         ..:|..|.|
  Fly  3360 V---GGSNVGGSLSSIVHSEEELTGSYNWDYLLDWGPQYQPLAHVFS---------EIARLKDDT 3412

Zfish  3611 FDLSVRSNDGVHSAVNS 3627
              ||..|..|..|:..|
  Fly  3413 --LSEHSGSGASSSAKS 3427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fat4	XP_021336971.1	Cadherin_repeat	30..113	CDD:206637	22/90 (24%)
		Cadherin_repeat	121..228	CDD:206637	41/106 (39%)
		Cadherin_repeat	236..330	CDD:206637	37/98 (38%)
		Cadherin_repeat	345..446	CDD:206637	34/100 (34%)
		Cadherin_repeat	454..550	CDD:206637	31/97 (32%)
		Cadherin_repeat	559..659	CDD:206637	32/99 (32%)
		Cadherin_repeat	667..763	CDD:206637	31/103 (30%)
		Cadherin_repeat	772..861	CDD:206637	33/94 (35%)
		Cadherin_repeat	876..964	CDD:206637	32/89 (36%)
		Cadherin_repeat	972..1068	CDD:206637	38/108 (35%)
		Cadherin_repeat	1077..1178	CDD:206637	34/100 (34%)
		Cadherin_repeat	1186..1283	CDD:206637	32/99 (32%)
		Cadherin_repeat	1293..1388	CDD:206637	29/110 (26%)
		Cadherin_repeat	1400..1497	CDD:206637	5/96 (5%)
		Cadherin_repeat	1503..1594	CDD:206637	11/90 (12%)
		Cadherin_repeat	1606..1692	CDD:206637	7/85 (8%)
		Cadherin_repeat	<1697..1765	CDD:206637	20/75 (27%)
		Cadherin_repeat	1773..1868	CDD:206637	29/102 (28%)
		Cadherin_repeat	1876..1974	CDD:206637	31/98 (32%)
		Cadherin_repeat	1982..2078	CDD:206637	13/95 (14%)
		Cadherin_repeat	2086..2182	CDD:206637	39/95 (41%)
		Cadherin_repeat	2191..2288	CDD:206637	9/96 (9%)
		Cadherin_repeat	2296..2392	CDD:206637	39/96 (41%)
		Cadherin_repeat	2400..2487	CDD:206637	29/91 (32%)
		Cadherin_repeat	2504..2595	CDD:206637	30/146 (21%)
		Cadherin_repeat	2603..2699	CDD:206637	38/97 (39%)
		Cadherin_repeat	2706..2798	CDD:206637	26/99 (26%)
		Cadherin_repeat	2812..2909	CDD:206637	30/106 (28%)
		Cadherin_repeat	2917..3015	CDD:206637	25/103 (24%)
		Cadherin_repeat	3025..3122	CDD:206637	30/98 (31%)
		Cadherin_repeat	3130..3225	CDD:206637	28/99 (28%)
		Cadherin_repeat	3234..3332	CDD:206637	32/102 (31%)
		Cadherin_repeat	3341..3438	CDD:206637	18/123 (15%)
		Cadherin_repeat	3446..3542	CDD:206637	22/121 (18%)
		EGF	3737..3792	CDD:238010
		EGF_CA	3794..3830	CDD:238011
		EGF_CA	3832..3867	CDD:238011
		EGF_CA	3871..3906	CDD:238011
		LamG	3909..4072	CDD:238058
		EGF_CA	4098..4130	CDD:238011
		Laminin_G_2	4182..4305	CDD:308045
		EGF_CA	4360..4394	CDD:238011
ds	NP_001285551.1	CA	111..172	CDD:214520	16/63 (25%)
		Cadherin_repeat	178..282	CDD:206637	41/106 (39%)
		Cadherin_repeat	291..389	CDD:206637	37/97 (38%)
		Cadherin_repeat	406..500	CDD:206637	34/97 (35%)
		Cadherin_repeat	509..607	CDD:206637	32/97 (33%)
		Cadherin_repeat	616..711	CDD:206637	32/98 (33%)
		Cadherin_repeat	719..820	CDD:206637	30/100 (30%)
		Cadherin_repeat	832..927	CDD:206637	33/94 (35%)
		Cadherin_repeat	937..1032	CDD:206637	33/94 (35%)
		Cadherin_repeat	1040..1149	CDD:206637	38/108 (35%)
		Cadherin_repeat	1158..1252	CDD:206637	34/100 (34%)
		Cadherin_repeat	1263..1361	CDD:206637	32/99 (32%)
		Cadherin_repeat	1369..1481	CDD:206637	30/112 (27%)
		Cadherin_repeat	1489..1598	CDD:206637	43/370 (12%)
		Cadherin_repeat	1614..1710	CDD:206637	29/95 (31%)
		Cadherin_repeat	1723..1843	CDD:206637	44/202 (22%)
		Cadherin_repeat	1853..1948	CDD:206637	48/200 (24%)
		Cadherin_repeat	1957..2053	CDD:206637	39/95 (41%)
		Cadherin_repeat	2061..2154	CDD:206637	29/92 (32%)
		Cadherin_repeat	2170..2318	CDD:206637	30/147 (20%)
		Cadherin_repeat	2326..2424	CDD:206637	38/97 (39%)
		Cadherin_repeat	2434..2528	CDD:206637	26/96 (27%)
		Cadherin_repeat	2549..2641	CDD:206637	28/99 (28%)
		Cadherin_repeat	2652..2748	CDD:206637	25/103 (24%)
		Cadherin_repeat	2758..2858	CDD:206637	30/99 (30%)
		Cadherin_repeat	2866..2960	CDD:206637	28/95 (29%)
		Cadherin_repeat	2985..3071	CDD:206637	29/101 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D23733at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010