Protein Alignment CDK3 and CDC28

DIOPT Version :9

• Sequence 1: NP_001249.1
• Gene: CDK3 / 1018
• HGNCID: 1772
• Length: 305
• Species: Homo sapiens
• Sequence 2: NP_009718.3
• Gene: CDC28 / 852457
• SGDID: S000000364
• Length: 298
• Species: Saccharomyces cerevisiae
• Alignment Length: 288
• Identity: 187/288 - (64%)
• Similarity: 231/288 - (80%)
• Gaps: 5/288 - (1%)

Human     4 FQKVEKIGEGTYGVVYKAKNRETGQ---LVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVR 65
            ::::||:|||||||||||.:...||   :||||||||:.|.||||||||||||||||||..||||
Yeast     8 YKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVR 72

Human    66 LLDVVHNE-RKLYLVFEFLSQDLKKYMDSTPGSE-LPLHLIKSYLFQLLQGVSFCHSHRVIHRDL 128
            |.|:||:: .|||||||||..|||:||:..|..: |...::|.::.||.:|:::|||||::||||
Yeast    73 LYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDL 137

Human   129 KPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSIGCIF 193
            ||||||||:.|.:||.|||||||||||||.||||:|||||||||:|||.|.|:|.||.|||||||
Yeast   138 KPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIF 202

Human   194 AEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSFPKWTRKGLEEIVPNLEPE 258
            |||..||.:|.|||||||:|:|||:||||:|..||.:..|||:|.|||:|.||.|.::||:|:|.
Yeast   203 AEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPR 267

Human   259 GRDLLMQLLQYDPSQRITAKTALAHPYF 286
            |.|||.:||.|||..||:|:.|..||||
Yeast   268 GIDLLDKLLAYDPINRISARRAAIHPYF 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK3	NP_001249.1	PLN00009	1..293	CDD:177649	187/288 (65%)
		STKc_CDK2_3	3..286	CDD:270844	185/286 (65%)
CDC28	NP_009718.3	STKc_CDK1_CdkB_like	8..295	CDD:270829	185/286 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C159051537
Domainoid	1	1.000	387	1.000	Domainoid score	I115
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	387	1.000	Inparanoid score	I384
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	1	1.000	-	-		otm52745
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	1	1.100	-	-	O	PTHR24056
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X960
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.750