Protein Alignment RBM7 and SC35

DIOPT Version :10

• Sequence 1: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Sequence 2: NP_652612.1
• Gene: SC35 / 53444
• FlyBaseID: FBgn0265298
• Length: 195
• Species: Drosophila melanogaster
• Alignment Length: 187
• Identity: 53/187 - (28%)
• Similarity: 78/187 - (41%)
• Gaps: 31/187 - (16%)

Human    11 TLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDK-DGKPKQFAFVNFKHEVSVPYAMNLLNGIK 74
            :|.|.||..:.|.|.|..:|.:.|.|..:.||:|: ..:.:.||||.|..:.....|:..::|..
  Fly    24 SLKVDNLTYRTTPEDLRRVFERCGEVGDIYIPRDRYTRESRGFAFVRFYDKRDAEDALEAMDGRM 88

Human    75 LYGRPIKIQF-RSGSSHAPQDVSLSYPQHHVGNSS-----PTSTSPSSRYERTMDNMTSSAQIIQ 133
            |.||.:::|. |.|...:|...|........|..|     ..|.||..|..|:..         :
  Fly    89 LDGRELRVQMARYGRPSSPTRSSSGRRGGGGGGGSGGRRRSRSRSPMRRRSRSPR---------R 144

Human   134 RSFS--------SPENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSV-QSHSHS 181
            ||:|        |||  :|.....|.:|..|..| .||.   ..|.:|:. :|.|.|
  Fly   145 RSYSRSRSPGSHSPE--RRSKFSRSPVRGDSRNG-IGSG---SGGLAPAASRSRSRS 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005	23/72 (32%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35		2/9 (22%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76		2/16 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		6/20 (30%)
SC35	NP_652612.1	RRM_SRSF2_SRSF8	25..97	CDD:409751	23/71 (32%)