Protein Alignment RBM7 and Hrb98DE

DIOPT Version :10

• Sequence 1: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Sequence 2: NP_524543.1
• Gene: Hrb98DE / 43385
• FlyBaseID: FBgn0001215
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 222
• Identity: 46/222 - (20%)
• Similarity: 77/222 - (34%)
• Gaps: 48/222 - (21%)

Human    10 RTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKD-KDGKPKQFAFVNFKHEVSVPYAMNLLNGI 73
            |.||:|.|:.:.|:|.|...|.:.|.::.|.:.|| :..:.:.|.|:.:.|...:..|..
  Fly    31 RKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFITYSHSSMIDEAQK----- 90

Human    74 KLYGRPIKIQFR--SGSSHAP-QDV-----SLSYPQHHVGNSSPTSTSPSSR-YERTMDNMTSSA 129
               .||.||..|  ......| ||:     ..:..:..||.........|.| |.:...|:....
  Fly    91 ---SRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDDHDEQSIRDYFQHFGNIVDIN 152

Human   130 QIIQRSFSSPENF----------------QRQAVMNSAL------------RQMSYGGKFGSSPL 166
            .:|.:.......|                |:|..:|..:            :|...||:.|  |.
  Fly   153 IVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMVDVKKALPKQNDQQGGGGGRGG--PG 215

Human   167 DQSGFSPSVQSHSHSFNQSSSSQWRQG 193
            .::|.:.......:..||:....|..|
  Fly   216 GRAGGNRGNMGGGNYGNQNGGGNWNNG 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005	20/73 (27%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35		2/9 (22%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76		2/16 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		6/31 (19%)
Hrb98DE	NP_524543.1	RRM1_hnRNPA_like	32..109	CDD:409992	21/84 (25%)
		RRM_SF	123..195	CDD:473069	11/71 (15%)