Protein Alignment RBM7 and Rb97D

DIOPT Version :10

• Sequence 1: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Sequence 2: NP_524520.1
• Gene: Rb97D / 43231
• FlyBaseID: FBgn0004903
• Length: 471
• Species: Drosophila melanogaster
• Alignment Length: 233
• Identity: 60/233 - (25%)
• Similarity: 86/233 - (36%)
• Gaps: 60/233 - (25%)

Human    10 RTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDK-DGKPKQFAFVNFKHEVSVPYA-MNLLNG 72
            :.||||.|:....||.|.|.|.|.|.|:.||:..|| .||.:.||||.|....:|..| :...:.
  Fly   123 KKLFVGGLKDNHDEECLREYFLQFGNVVSVKLLTDKTTGKRRGFAFVEFDDYDAVDKAILKKQHA 187

Human    73 IK---------LYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSS--PTST--SPSSR------- 117
            ||         :|....|.:.:.|........||:..|...|...  |...  :||.|
  Fly   188 IKYVHVDVKKSIYNLDKKEKQQPGGLANAIKPSLNQQQQQQGGGQQPPNGNMQAPSFRPPVPPQQ 252

Human   118 ----YERTMDNMTSSAQIIQRSFSSPENFQRQAVMNSAL---------RQMSYGGKFGSSPLDQS 169
                |::.......||        .|.||........|:         :||:..|.:  .|..|:
  Fly   253 AMGPYQQQPPPAPMSA--------PPPNFNYWGPPPPAMPPYYQQPPPQQMNGWGPY--PPPQQN 307

Human   170 GFS------PSVQSHSHSFNQSSSSQWRQGTPSSQRKV 201
            |::      |..|       |..::||  |.|...::|
  Fly   308 GWNAPPPPPPGAQ-------QWHANQW--GCPPPVQQV 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005	30/83 (36%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35		4/9 (44%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76		4/26 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		11/45 (24%)
Rb97D	NP_524520.1	RRM2_hnRNPA_like	124..196	CDD:409766	28/71 (39%)
		RRM_SF	33..110	CDD:473069