Protein Alignment RBM7 and Rox8

DIOPT Version :10

• Sequence 1: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Sequence 2: NP_732944.2
• Gene: Rox8 / 42848
• FlyBaseID: FBgn0005649
• Length: 470
• Species: Drosophila melanogaster
• Alignment Length: 217
• Identity: 53/217 - (24%)
• Similarity: 93/217 - (42%)
• Gaps: 46/217 - (21%)

Human    10 RTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHEVSVPYAMNLLNGIK 74
            :||:||||::.|:|:||..||...|||...||.::....|  :||:.:.:..:...|:..:|...
  Fly     7 KTLYVGNLDSSVSEDLLIALFSTMGPVKSCKIIREPGNDP--YAFIEYSNYQAATTALTAMNKRL 69

Human    75 LYGRPIKIQFRSGSSHAPQ-DVSLSYPQHH--VGNSSPTSTSPSSRYERTMDNMTSSAQIIQRSF 136
            ...:.||:.:.:...:.|: |:|   ..||  ||:.||...:.:.|.........|:.:|::...
  Fly    70 FLEKEIKVNWATSPGNQPKTDIS---SHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPH 131

Human   137 SSPE------NFQRQAVMNSALRQMS-----------------------------YGGKFGSSPL 166
            :...      :|.::|...:|::.|:                             .||..|..|.
  Fly   132 TMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPG 196

Human   167 DQSGFSPSVQSHSHS--FNQSS 186
            :.||...| |.|:..  :||||
  Fly   197 NGSGVKGS-QRHTFEEVYNQSS 217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005	24/72 (33%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35		4/9 (44%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76		2/16 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		10/26 (38%)
Rox8	NP_732944.2	RRM1_TIA1_like	9..80	CDD:409788	23/72 (32%)
		RRM2_TIA1_like	96..170	CDD:409789	12/73 (16%)
		RRM_SF	221..292	CDD:473069