Protein Alignment RBM7 and RnpS1

DIOPT Version :10

• Sequence 1: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Sequence 2: NP_649903.1
• Gene: RnpS1 / 41147
• FlyBaseID: FBgn0037707
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 185
• Identity: 46/185 - (24%)
• Similarity: 71/185 - (38%)
• Gaps: 38/185 - (20%)

Human    12 LFVGNLETKVTEELLFELFHQAGPVIKVKIPKDK--DGKPKQFAFVNFKHEVSVPYAMNLLNGIK 74
            :.||.|...||::.:||:|...|.|..|:.|.|:  ....:..|||.:........||..::|.:
  Fly   221 IHVGRLTRNVTKDHVFEIFSSFGDVKNVEFPVDRFHPNFGRGVAFVEYATPEDCESAMKHMDGGQ 285

Human    75 LYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSSRYERTMDNMTSSAQIIQRSFSSP 139
            :.|               |::::| |...| ...|....||....|..:|          .:.||
  Fly   286 IDG---------------QEITVS-PVVLV-KQRPPMRRPSPPMRRPQNN----------RWRSP 323

Human   140 ENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSVQSHS-----HSFNQSSSSQ 189
            ..|.|   .|:.......||....||: ::..||..:|.|     ...|.|.||:
  Fly   324 PQFNR---FNNRGGGGGGGGGRRQSPM-RNRRSPRRRSRSPIRRRRRSNSSDSSR 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005	20/72 (28%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35		3/9 (33%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76		3/16 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		10/32 (31%)
RnpS1	NP_649903.1	RRM_RNPS1	221..294	CDD:409800	21/87 (24%)