Protein Alignment RBM7 and lark

DIOPT Version :10

• Sequence 1: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Sequence 2: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 64/286 - (22%)
• Similarity: 95/286 - (33%)
• Gaps: 75/286 - (26%)

Human    12 LFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHEVSVPYAMNLLNGIKLY 76
            :|||||..|.....:.|||.:.|.|::..|.::       :.||:......|..|:..|||..:.
  Fly    88 IFVGNLTDKTRAPEVRELFQKYGTVVECDIVRN-------YGFVHLDCVGDVQDAIKELNGRVVD 145

Human    77 GRPIKIQ------------------FRSG-SSHAPQDVSLSYPQHHVGNSSPTSTS--------- 113
            |:|:|:|                  :|.| |.|..::....|.....|...|:..|
  Fly   146 GQPLKVQVSTSRVRPKPGMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGGYRDRMY 210

Human   114 -----------PSSRYERTMDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYGGKFGSSPLD 167
                       |....:|.||.. .......|.|....:...:....|.:|.      |...|:.
  Fly   211 GRDPYPPPPPPPPFLRDRIMDGF-RDYDYYDRRFEDSRDLYERRYQTSRMRD------FPPPPIS 268

Human   168 QSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGK 232
            :....|...:.|.|....|.|: ...|..|:|    :..|..:....||....|.||
  Fly   269 RREPMPLPPTLSGSLRSCSVSR-GYDTMFSRR----SPPPPRSSNGMSRYGSPTPHG-------- 320

Human   233 RDDFFYEDRNHDDWSHDYDNRRDSSR 258
                 |||.:.|    .:|.|..|||
  Fly   321 -----YEDFSRD----AFDERMISSR 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005	22/70 (31%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35		3/9 (33%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76		5/16 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		24/96 (25%)
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779
		RRM1_2_CoAA_like	87..152	CDD:409779	22/70 (31%)
		hnRNP-R-Q	<88..>258	CDD:273732	37/177 (21%)