Protein Alignment RBM7 and Ref2

DIOPT Version :10

• Sequence 1: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Sequence 2: NP_609574.1
• Gene: Ref2 / 34667
• FlyBaseID: FBgn0032439
• Length: 220
• Species: Drosophila melanogaster
• Alignment Length: 177
• Identity: 41/177 - (23%)
• Similarity: 66/177 - (37%)
• Gaps: 58/177 - (32%)

Human    12 LFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHEVSVPYAMNLLNGIKLY 76
            :.|.||:..|.::.:.|||:|.|.|.|..:..|:||.....|.::||:.......:...:|::|.
  Fly    77 VMVCNLDYGVDDDDIMELFNQDGVVEKGFVHYDRDGNSLGTAHLSFKYREEAFQIIEQFHGVRLD 141

Human    77 GRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSSRYERTMDNMTSSAQIIQRSFSSPEN 141
            ||.:|:                   |.|.|:                                .|
  Fly   142 GRRLKL-------------------HLVQNT--------------------------------RN 155

Human   142 FQRQAVMNSALRQMSY------GGKFGSSPLDQSGFSPSVQSHSHSF 182
            |:|..|.:.:||..|:      .|.|.:..| |:||..|....:.||
  Fly   156 FKRTDVDDLSLRMGSFKTRFLQNGTFKTRSL-QNGFQKSRLFRNSSF 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005	22/70 (31%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35		4/9 (44%)
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76		1/16 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		7/20 (35%)
Ref2	NP_609574.1	RRM_SF	75..149	CDD:473069	22/90 (24%)