DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42764 and Crisp2

DIOPT Version :9

Sequence 1:	NP_001189140.1	Gene:	CG42764 / 10178963	FlyBaseID:	FBgn0261832	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001191000.1	Gene:	Crisp2 / 22024	MGIID:	98815	Length:	243	Species:	Mus musculus

Alignment Length:	200	Identity:	48/200 - (24%)
Similarity:	75/200 - (37%)	Gaps:	59/200 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLLFLFFLAFRPCL-------------GYNVIRSEAYDAHNDHRRTWVVPELIESDELSHDAEEY 52
            ::||:|.|..|..|             ....::.|..:.||:.||: |.|  ..||.|.   .|:
Mouse     6 VMLFVFALLLRSPLTEGKDPDFTSLLTNQLQVQREIVNKHNELRRS-VNP--TGSDILK---MEW 64

  Fly    53 AIHLATLNIPDQ----ILYETAKDR---NIRVDHLDYPLSEPE------NDFYTENICEFIRNEC 104
            :|. ||.|....    ||..::||.   |||.....|..::|.      ..:|.||. :|:
Mouse    65 SIQ-ATTNAQKWANKCILEHSSKDDRKINIRCGENLYMSTDPTLWSTVIQSWYNENE-DFV---- 123

  Fly   105 VYYWASEGAASYGIAKERRTKVEQSLADKFSAITWKSTTEMGVG--WAPKDRSKKGGRKILVVRY 167
                       ||:..:     ..|....::.:.|.|:.::|.|  :.|...:.|   ...|..|
Mouse   124 -----------YGVGAK-----PNSAVGHYTQLVWYSSFKIGCGIAYCPNQDNLK---YFYVCHY 169

  Fly   168 SPAGN 172
            .|.||
Mouse   170 CPMGN 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42764	NP_001189140.1	SCP	22..172	CDD:294090	40/164 (24%)
Crisp2	NP_001191000.1	SCP_CRISP	36..171	CDD:240183	39/165 (24%)
Crisp2	NP_001191000.1	Crisp	189..243	CDD:285731
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110