DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42764 and GLIPR1L2

DIOPT Version :9

Sequence 1:	NP_001189140.1	Gene:	CG42764 / 10178963	FlyBaseID:	FBgn0261832	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_001257325.1	Gene:	GLIPR1L2 / 144321	HGNCID:	28592	Length:	344	Species:	Homo sapiens

Alignment Length:	269	Identity:	56/269 - (20%)
Similarity:	90/269 - (33%)	Gaps:	107/269 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SEAYDAHNDHR------------RTWVVPELIESDELSHDAEEYAIH-LATLNIPDQILYETAKD 72
            :|..:.||:.|            .||.|       .||..|..:... |.|.||..|
Human    55 NEYVNLHNELRGDVIPRGSNLRFMTWDV-------ALSRTARAWGKKCLFTHNIYLQ-------- 104

  Fly    73 RNIRVDHLD-YPLSE-----PENDFYTENICEFIRNECVYYWASE--------GAASYGIAKERR 123
             ::::.|.. |.:.|     |||:| |.:|.  ||:     |.:|        |:.|
Human   105 -DVQMVHPKFYGIGENMWVGPENEF-TASIA--IRS-----WHAEKKMYNFENGSCS-------- 152

  Fly   124 TKVEQSLADKFSAITWKSTTEMGVGWAPKDRSKKG---GRKILVVRYSPAGN------QPGEYAE 179
                 .....:..:.|..:.::|....|  .||.|   ...|.:..|:|.|.      :||.:..
Human   153 -----GDCSNYIQLVWDHSYKVGCAVTP--CSKIGHIIHAAIFICNYAPGGTLTRRPYEPGIFCT 210

  Fly   180 NIGD----TEFL---------EYFKM---------PTREDPDRWRNGSARLSYGVVDVQI-CISL 221
            ..|.    |:||         .|::.         |...||         |...::.::| |..|
Human   211 RCGRRDKCTDFLCSNADRDQATYYRFWYPKWEMPRPVVCDP---------LCTFILLLRILCFIL 266

  Fly   222 LVLTITFIR 230
            .|:|:..::
Human   267 CVITVLIVQ 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42764	NP_001189140.1	SCP	22..172	CDD:294090	39/179 (22%)
GLIPR1L2	NP_001257325.1	SCP_GLIPR-1_like	52..195	CDD:240185	38/178 (21%)
GLIPR1L2	NP_001257325.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	292..344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010