DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42780 and CRISPLD2

DIOPT Version :9

Sequence 1:	NP_001284979.1	Gene:	CG42780 / 10178796	FlyBaseID:	FBgn0261848	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_113664.1	Gene:	CRISPLD2 / 83716	HGNCID:	25248	Length:	497	Species:	Homo sapiens

Alignment Length:	221	Identity:	57/221 - (25%)
Similarity:	79/221 - (35%)	Gaps:	65/221 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 DKNALIKAHNLVRQKWASGKAKIKWTACKMAKMEWNKDLEKLAILNAKTCLMGHDECHNTEKFRL 125
            ||..::..||.:|       .:::..|..|..|.|:.:|||.|...|..|:..|..   |.....
Human    55 DKEEILMLHNKLR-------GQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGP---TSLLVS 109

  Fly   126 SGQNLFA-------MGFSHARITKTKMNMTLSMLFEMAVQKWAGEEKDITAEDLKKTTPNPPE-- 181
            .||||.|       .||.                    ||.|..|.||.|.....:..|..||
Human   110 IGQNLGAHWGRYRSPGFH--------------------VQSWYDEVKDYTYPYPSECNPWCPERC 154

  Fly   182 ---VIGHLTVLINEKSNAVGCGLVAYNL-------GEI--RRYNLACNYA-YTNVIGERVYE--- 230
               :..|.|.::...:|.:||   |.|.       ||:  ......|||: ..|.|||..|:
Human   155 SGPMCTHYTQIVWATTNKIGC---AVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGR 216

  Fly   231 ---ECAKA-GIECAKGI---DQKYPP 249
               ||..: |..|...:   ::.|.|
Human   217 PCSECPPSYGGSCRNNLCYREETYTP 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42780	NP_001284979.1	SCP_euk	62..219	CDD:240180	44/177 (25%)
CRISPLD2	NP_113664.1	SCP_euk	56..201	CDD:240180	44/177 (25%)
		LCCL	286..370	CDD:128866
		LCCL	387..479	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151223
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850