DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42780 and PI16

DIOPT Version :9

Sequence 1:	NP_001284979.1	Gene:	CG42780 / 10178796	FlyBaseID:	FBgn0261848	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	193	Identity:	57/193 - (29%)
Similarity:	91/193 - (47%)	Gaps:	38/193 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 DKNALIKAHNLVRQKWASGKAKIKWTACKMAKMEWNKDLEKLAILNAKTCLMGHDECHNTEKFRL 125
            :|..:::.|||.|       |::..||..|..|.|:::|...|...|:.|:.|    ||.|:.|
Human    32 EKRLMVELHNLYR-------AQVSPTASDMLHMRWDEELAAFAKAYARQCVWG----HNKERGR- 84

  Fly   126 SGQNLFAMGFSHARITKTKMNMTLSMLFEMAVQKWAGEEKDITAEDLKKTTPNPPEVIGHLTVLI 190
            .|:||||       ||...|::.|:|      ::|..|.:..   :|...|.:|.::.||.|.::
Human    85 RGENLFA-------ITDEGMDVPLAM------EEWHHEREHY---NLSAATCSPGQMCGHYTQVV 133

  Fly   191 NEKSNAVGCGL-VAYNLGEIRRYN---LACNYAYT-NVIGERVYEE---CAK--AGIECAKGI 243
            ..|:..:|||. ....|..:...|   |.|||... ||.|:|.|:|   |::  :|..|...:
Human   134 WAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHCKNSL 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42780	NP_001284979.1	SCP_euk	62..219	CDD:240180	47/160 (29%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	47/160 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2340
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920