Protein Alignment RCL1 and Rtc1

DIOPT Version :10

• Sequence 1: NP_005763.3
• Gene: RCL1 / 10171
• HGNCID: 17687
• Length: 373
• Species: Homo sapiens
• Sequence 2: NP_572919.1
• Gene: Rtc1 / 32338
• FlyBaseID: FBgn0020909
• Length: 384
• Species: Drosophila melanogaster
• Alignment Length: 378
• Identity: 204/378 - (53%)
• Similarity: 269/378 - (71%)
• Gaps: 8/378 - (2%)

Human     1 MATQAHSLSYAGCNFLRQRLVLSTLSGRPVKIRKIRARDDN-PGLRDFEASFIRLLDKITNGSRI 64
            :|.:.:.|.|.|.|||:|||:|:.|||:||||.:||:.|:. ||||::|.|.||||||||||::|
  Fly     4 IAQEGNCLIYRGSNFLKQRLILACLSGKPVKISQIRSEDETAPGLREYEISLIRLLDKITNGTKI 68

Human    65 EINQTGTTLYYQPGLLYGGSVEHDCSVLRGIGYYLESLLCLAPFMKHPLKIVLRGVTNDQVDPSV 129
            |:|..||::.:.||||:||.:.|||.|.|||||||::|:.|.||.|.||:..||||||.:..|||
  Fly    69 ELNPAGTSVMFSPGLLHGGQLNHDCCVQRGIGYYLDALIALGPFCKSPLQCTLRGVTNSKDSPSV 133

Human   130 DVLKATALPLLKQFGIDGESFELKIVRRGMPPGGGGEVVFSCPVRKVLKPIQLTDPGKIKRIRGM 194
            |.:|..||.|||:|.:..|..|||:||||:.|.||||::|.|||||.|:.||....|.:|||||.
  Fly   134 DHIKGAALSLLKRFLLVDEGLELKVVRRGVAPLGGGEIIFRCPVRKSLRAIQFQSQGMVKRIRGT 198

Human   195 AYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGVNSGKSPGFGLSLVAETTSGTFLSAEL 259
            .|:.:|||.||||.|::|:..:.||:||:|||||..||..||.|||||:.|:||||.|...:|:.
  Fly   199 VYACKVSPAMANRTVEAAKGCMLKFLPDVYIYTDQNKGKMSGNSPGFGICLIAETTDGVCFAADC 263

Human   260 ASN--PQGQGAAVLPEDLGRNCARLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPLSP 322
            .||  .:.:....:||:||:..|..||:||||||||||:.|.||.|.:.|||:.|||.|.|.||.
  Fly   264 CSNTREESEDTPSIPENLGKEVALRLLDEIYRGGCVDSSYQWLAALYIALGQKHVSKFLTGALSN 328

Human   323 YTIEFLRHLKSFFQIMFKIETKPC-----GEELKGGDKVLMTCVGIGFSNLSK 370
            ||:.||:||:.||.|.||:|....     .|.::|..||||.|||||::|::|
  Fly   329 YTVHFLQHLRDFFSITFKLENPEAEDEDEAENVRGAQKVLMACVGIGYTNINK 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RCL1	NP_005763.3	18S_RNA_Rcl1p	8..371	CDD:274564	203/371 (55%)
Rtc1	NP_572919.1	18S_RNA_Rcl1p	11..384	CDD:274564	203/371 (55%)