Protein Alignment CDK2 and Cdk1

DIOPT Version :9

• Sequence 1: XP_011536034.1
• Gene: CDK2 / 1017
• HGNCID: 1771
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 185/340 - (54%)
• Similarity: 227/340 - (66%)
• Gaps: 59/340 - (17%)

Human     1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVK 65
            ||:|:|:|||||||||||||.||:|||::||:|||||:::.|||||||||||||||||.|.|||.
  Fly     1 MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVC 65

Human    66 LLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPL------PLIKSYLFQLLQGLAFCHSHRVL 124
            |.||:..||::||:||||..||||:||:     :|:      .|::|||:|:...:.|||..|||
  Fly    66 LEDVLMEENRIYLIFEFLSMDLKKYMDS-----LPVDKHMESELVRSYLYQITSAILFCHRRRVL 125

Human   125 HRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSL 189
            |||||||||||:..|.||:|||||.|:||:|||.||||:|||||||||:|||...||..|||||:
  Fly   126 HRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSI 190

Human   190 GCIFAEMHLVGTQHHARCCGEHRRNGRQSLCPLCSYLEVAASQGWGMTAVSTPYPVTRRALFPGD 254
            |||||||                                                .||:.||.||
  Fly   191 GCIFAEM------------------------------------------------ATRKPLFQGD 207

Human   255 SEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDP 319
            ||||||||:||.|.||.|.:||||||:||||.:||.|:....:..:..||.:|..|:.:||.|||
  Fly   208 SEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDP 272

Human   320 NKRISAKAALAHPFF 334
            ..|||||..|.||:|
  Fly   273 VHRISAKDILEHPYF 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK2	XP_011536034.1	STKc_CDK2_3	3..334	CDD:270844	182/336 (54%)
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	182/336 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	1	1.000	-	-		FOG0000411
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100334
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R185
SonicParanoid	1	1.000	-	-		X960
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.750