Protein Alignment CDK2 and cdc2

DIOPT Version :10

• Sequence 1: XP_011536034.1
• Gene: CDK2 / 1017
• HGNCID: 1771
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_001342995.1
• Gene: cdc2 / 2539869
• PomBaseID: SPBC11B10.09
• Length: 297
• Species: Schizosaccharomyces pombe
• Alignment Length: 343
• Identity: 194/343 - (56%)
• Similarity: 238/343 - (69%)
• Gaps: 55/343 - (16%)

Human     1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKEL----NHP 61
            |||:||||||||||||||||||:||:|.:||:|||||:.|:||||||||||||||||:    |..
pombe     1 MENYQKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENNRS 65

Human    62 NIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG---IPLPLIKSYLFQLLQGLAFCHSHRV 123
            |.|:|||::|.|:|||||||||..||||:||..:.||   :...|::.:.:||:.|:.||||.|:
pombe    66 NCVRLLDILHAESKLYLVFEFLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHSRRI 130

Human   124 LHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWS 188
            :|||||||||||:.||.:|||||||||:||||:|.||||:|||||||||:|||.::|||.|||||
pombe   131 IHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNYTHEIVTLWYRAPEVLLGSRHYSTGVDIWS 195

Human   189 LGCIFAEMHLVGTQHHARCCGEHRRNGRQSLCPLCSYLEVAASQGWGMTAVSTPYPVTRRALFPG 253
            :|||||||                                                :.|..||||
pombe   196 VGCIFAEM------------------------------------------------IRRSPLFPG 212

Human   254 DSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYD 318
            |||||::|:||:.||||:|.||||||.:.|||.:||:|.|.|..||||..:||...|||.||.||
pombe   213 DSEIDEIFKIFQVLGTPNEEVWPGVTLLQDYKSTFPRWKRMDLHKVVPNGEEDAIELLSAMLVYD 277

Human   319 PNKRISAKAALAHPFFQD 336
            |..|||||.||...:.:|
pombe   278 PAHRISAKRALQQNYLRD 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK2	XP_011536034.1	STKc_CDK2_3	3..334	CDD:270844	191/337 (57%)
cdc2	NP_001342995.1	STKc_CDK1_CdkB_like	4..293	CDD:270829	190/336 (57%)