DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment LPCAT3 and nes

DIOPT Version :10

Sequence 1:NP_005759.4 Gene:LPCAT3 / 10162 HGNCID:30244 Length:487 Species:Homo sapiens
Sequence 2:NP_524157.2 Gene:nes / 40093 FlyBaseID:FBgn0026630 Length:497 Species:Drosophila melanogaster


Alignment Length:449 Identity:167/449 - (37%)
Similarity:259/449 - (57%) Gaps:25/449 - (5%)


- Green bases have known domain annotations that are detailed below.


Human    28 LNKLATSLGASEQALRLIISIFLGYPFALFYRHYL-FYKETYLIHLFHTFTGLSIAYFNFGNQLY 91
            ::.:|:.:|...:||||:::|..|||.|..|:.:: ...:..:.|:|....|..:.|||:|...|
  Fly    14 MDGIASGVGVPVEALRLLLTILAGYPVAALYQKFISVIADKTVHHMFFAGCGAGLCYFNYGLDTY 78

Human    92 HSLLCIV-LQFLILRLMGRTITAVLTTFCFQMAYLLAGYYYTATGNYDIKWTMPHCVLTLKLIGL 155
            |||:.|: ..||:|.|..:|...:...|.|.|:|||.||:||::.:|||.||||||:|.|::||.
  Fly    79 HSLIAILTTYFLVLLLRKKTQIFLAINFVFHMSYLLLGYFYTSSNDYDILWTMPHCILVLRMIGY 143

Human   156 AVDYFDGGKDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIP 220
            ..|..||.|:::.||.:|::.|::..|||||:..||||...|||||||....|...|.||.....
  Fly   144 GFDITDGLKEESELSKDQKETALKKPPSLLELLAFSYFPSGFLVGPQFPFRRYKAFVDGEFRQHE 208

Human   221 GKIPNSIIPALKRLSLGLFYLVGYTLLSPHITEDYLLTEDYDNHPFWFRCMYMLIWGKFVLYKYV 285
            |.:...:    :|...|.|||:...:...::.:.|.||.::....|..|...:..|.||.||||:
  Fly   209 GNVEAGV----RRFGAGAFYLIVCQVGLRYLPDSYFLTPEFAQVSFVKRIYLLGFWAKFSLYKYI 269

Human   286 TCWLVTEGVCILTGLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTIASFNINTNAWVARYIF 350
            :|||:|||..|..||.:.|.::.|:..|..|:|:|:.|.||.......:.|||:|||.||.:||:
  Fly   270 SCWLLTEGALICIGLTYKGEDKNGQPDWSGCSNVKLKLLETGNTMEHYVQSFNVNTNQWVGQYIY 334

Human   351 KRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARL-----------IQES 404
            ||||||.|:.:|.|.:|.|||:|||.||||.:.|.||:::|..|:|..|.           |..:
  Fly   335 KRLKFLNNRTISYGAALGFLAVWHGYHSGYYMTFLMEYMVVSTEKQITRFYTKVVLPQWGHILNN 399

Human   405 PTLSKLAAITVLQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHIFFL 463
            ..:.||        .|::..::.:.::||:.:|||....:::|:.||.::.:.|..|.:
  Fly   400 SDIYKL--------LYFITLKSYNVVYMGWCLTAFVFLKYERWIVVYGAVSYYGFTFLV 450

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LPCAT3NP_005759.4 MBOAT 24..487 CDD:445070 167/449 (37%)
Di-lysine motif 484..487
nesNP_524157.2 MBOAT 114..421 CDD:427117 124/318 (39%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.