Protein Alignment ATP6AP2 and atp6ap2

DIOPT Version :10

• Sequence 1: NP_005756.2
• Gene: ATP6AP2 / 10159
• HGNCID: 18305
• Length: 350
• Species: Homo sapiens
• Sequence 2: XP_009294369.1
• Gene: atp6ap2 / 406296
• ZFINID: ZDB-GENE-040426-1960
• Length: 398
• Species: Danio rerio
• Alignment Length: 361
• Identity: 241/361 - (66%)
• Similarity: 297/361 - (82%)
• Gaps: 14/361 - (3%)

Human     2 AVFVVLLALVAGVLGNEFSILKSPGSVVFRNGNWPIPGERIPDVAALSMGFSVKEDLSWPGLAVG 66
            ||| .|:.|::||||:..::|:||..|.||:..|||.||:|||:.||:|||||:|||.|||||.|
Zfish    40 AVF-ALIGLLSGVLGDSLTVLRSPQYVTFRDEQWPISGEKIPDLVALTMGFSVREDLDWPGLAAG 103

Human    67 NLFHRPRATVMVMVKGVNKLALPPGSVISYPLENAVPFSLDSVANSIHSLFSEETPVVLQLAPSE 131
            :||.||||..:::|:|::.|..|. :|.||||||.|||:||||||:||:||::.|||||||||||
Zfish   104 SLFQRPRANALIVVRGIDSLDFPK-NVSSYPLENPVPFTLDSVANTIHTLFADSTPVVLQLAPSE 167

Human   132 ERVYMVGKANSVFEDLSVTLRQLRNRLFQENSVLSSLPLNSLSRNNEVDLLFLSELQVLHDISSL 196
            ||:||:|.||:|||||.|||:|:|.||.|:.|||:||||.|||||||.|||||||:|||:|||:|
Zfish   168 ERLYMMGMANTVFEDLPVTLQQIRGRLSQDGSVLTSLPLVSLSRNNEADLLFLSEVQVLYDISAL 232

Human   197 LSRHKHLAKDHSPDLYSLELAGLDEIGKRYGEDSEQFRDASKILVDALQKFADDMYSLYGGNAVV 261
            |.:|||||||.:|||||||||||:||.:|||.||.|:.||.:||..||||||||:.|:||.||||
Zfish   233 LQKHKHLAKDPAPDLYSLELAGLEEIVRRYGTDSPQYTDAIRILTIALQKFADDVSSVYGNNAVV 297

Human   262 ELVTVKSFDTSLIRKTRTILEAKQ------------AKNPASPYNLAYKYNFEYSVVFNMVLWIM 314
            |:||||:|:..|.||:|:|||:||            ..||.|||||||||||:|:|:||:|||:|
Zfish   298 EVVTVKTFEVPLTRKSRSILESKQMGSRRTNRFKNVPSNPGSPYNLAYKYNFDYAVIFNIVLWLM 362

Human   315 IALALAVIITSYNIWNMDPGYDSIIYRMTNQKIRMD 350
            |.||||||..|||:||||||||||||||||||||:|
Zfish   363 IVLALAVIAISYNLWNMDPGYDSIIYRMTNQKIRLD 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6AP2	NP_005756.2	Renin_r	254..350	CDD:462287	72/107 (67%)
		Mediates retrograde transport to the ER. /evidence=ECO:0000269|PubMed:29127204	346..350		3/3 (100%)
atp6ap2	XP_009294369.1	Renin_r	290..398	CDD:462287	72/107 (67%)