| Sequence 1: | NP_004924.1 | Gene: | CDH15 / 1013 | HGNCID: | 1754 | Length: | 814 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001027277.1 | Gene: | CadN / 35070 | FlyBaseID: | FBgn0015609 | Length: | 3101 | Species: | Drosophila melanogaster |
| Alignment Length: | 1631 | Identity: | 283/1631 - (17%) |
|---|---|---|---|
| Similarity: | 417/1631 - (25%) | Gaps: | 956/1631 - (58%) |
- Green bases have known domain annotations that are detailed below.
|
Human 50 PPI---------SVSENHKRLPYPLVQIKS---DKQQLGSVIYSIQGPGVDEE--PRGVFSIDKF 100
Human 101 TGKVFLNAMLDREKTD---RFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAFTGRVL 162
Human 163 EGAVPGTYVTRAEATDADDP-ETDNAALRFSI------LQQGSPELFSIDELTGEIRTVQVGLDR 220
Human 221 EVVAVYNLTLQVADMSGDGLTATASAIITLDDINDNAPEFTRDEFFMEAIEAVSGVDVGRLEVED 285
Human 286 RDLPGSPNWVARFTILEGDPDGQFTIR------------TDPKTNEGV--LSIVKALDYE---SC 333
Human 334 EHYELKVSVQNEAPLQAAALRAERGQ-----------AKVRVHVQDTNE-PPVFQENPLRTSLAE 386
Human 387 GAPPGTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGGWYRA 451
Human 452 IV-------LAQDDASQPRTATGTLSIEILEVNDHAP---------------------VLA---- 484
Human 485 -------PP-------------------------------------------------------- 486
Human 487 ------------------------PPGS------------------------------------- 490
Human 491 ---------------------------------------------------LCSEPHQ-----GP 499
Human 500 GLLLGATDEDL---------------------------------------------PP------- 512
Human 513 -HGAPFH----------------------------------------------FQLSPRLPEL-- 528
Human 529 ----------------------------------------------------------------- 528
Human 529 ----GRNWS----LSQVNVSHARLRPRHQVPEGL------------------------------- 554
Human 555 -------------------------HRLSLL-----LR--------------DSGQPP------- 568
Human 569 QQREQ------------PLNV-------------------------------------------- 577
Human 578 --------------------TVCRCGKDGVCL-----------PG-------------------- 591
Human 592 ----------------------------------------------------------------- 591
Human 592 -----------------------AAAL-LAGGTG------------------------------- 601
Human 602 ----------------------------------------------------------------- 601
Human 602 ----------------------------------------------------------------- 601
Human 602 -----------LSLGALVIVLASALLLLVLVLLVALRARFWKQSRGKGLLH-GPQDDLRDNVLNY 654
Human 655 DEQGGGEEDQDAYDISQLRHPTALSLPLG---PPPLRRDAPQGRLHPQPPRVLPTSPL------D 710
Human 711 IADFINDGLEAADSDPSVPPYDTALIYDYEGDGSVAGTLSSILSSQGDEDQDYDYLRDWGPRFAR 775
Human 776 LADMYG 781 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CDH15 | NP_004924.1 | Cadherin_repeat | 52..148 | CDD:206637 | 28/112 (25%) |
| Cadherin_repeat | 157..256 | CDD:206637 | 42/105 (40%) | ||
| Cadherin_repeat | 271..371 | CDD:206637 | 24/127 (19%) | ||
| Cadherin_repeat | 379..479 | CDD:206637 | 29/106 (27%) | ||
| E_set | 487..580 | CDD:298831 | 43/517 (8%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 636..663 | 13/27 (48%) | |||
| Cadherin_C | 640..781 | CDD:279398 | 65/150 (43%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 676..703 | 10/29 (34%) | |||
| CadN | NP_001027277.1 | Cadherin_repeat | 178..301 | CDD:206637 | |
| Cadherin_repeat | 337..396 | CDD:206637 | |||
| E_set | 449..541 | CDD:298831 | |||
| Cadherin_repeat | 549..>625 | CDD:206637 | |||
| Cadherin_repeat | 655..752 | CDD:206637 | |||
| Cadherin_repeat | 765..853 | CDD:206637 | |||
| Cadherin_repeat | 862..964 | CDD:206637 | |||
| Cadherin_repeat | 973..1074 | CDD:206637 | |||
| Cadherin_repeat | 1083..1166 | CDD:206637 | |||
| Cadherin_repeat | <1219..1298 | CDD:206637 | |||
| Cadherin_repeat | 1310..1414 | CDD:206637 | |||
| Cadherin_repeat | 1423..1514 | CDD:206637 | |||
| Cadherin_repeat | 1522..1630 | CDD:206637 | 28/107 (26%) | ||
| Cadherin_repeat | 1638..1741 | CDD:206637 | 41/105 (39%) | ||
| Cadherin_repeat | 1762..1861 | CDD:206637 | 22/112 (20%) | ||
| Cadherin_repeat | 1871..1966 | CDD:206637 | 29/104 (28%) | ||
| Cadherin_repeat | 1974..2083 | CDD:206637 | 4/108 (4%) | ||
| EGF | 2350..2380 | CDD:278437 | 0/29 (0%) | ||
| LamG | 2385..2570 | CDD:238058 | 22/184 (12%) | ||
| EGF_2 | <2605..2631 | CDD:285248 | 5/25 (20%) | ||
| Laminin_G_2 | 2665..2800 | CDD:280389 | 7/134 (5%) | ||
| EGF_CA | 2869..2907 | CDD:238011 | 0/37 (0%) | ||
| Cadherin_C | 2952..3088 | CDD:279398 | 65/149 (44%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 130 | 1.000 | Domainoid score | I5199 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S8035 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.860 | |||||