Protein Alignment ARL4A and Arl4

DIOPT Version :10

• Sequence 1: NP_005729.1
• Gene: ARL4A / 10124
• HGNCID: 695
• Length: 200
• Species: Homo sapiens
• Sequence 2: NP_001245408.1
• Gene: Arl4 / 43771
• FlyBaseID: FBgn0039889
• Length: 313
• Species: Drosophila melanogaster
• Alignment Length: 298
• Identity: 121/298 - (40%)
• Similarity: 154/298 - (51%)
• Gaps: 109/298 - (36%)

Human    10 SILSNLPS-FQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIKVTLGNSKTVTFHF 73
            :||..||| ..:.|:|:||||.|||||.||||:|::::|||||.|||.||::.|||.:|.|.|..
  Fly    14 NILDALPSQVATLHVVMLGLDSAGKTTALYRLKFDQYLNTVPTIGFNCEKVQCTLGKAKGVHFLV 78

Human    74 WDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITRISENQGVPVLIVANKQDL 138
            |||||||||||||:|||||||||:||:||||.|||||||.||.:..:..:||||||||:||||||
  Fly    79 WDVGGQEKLRPLWRSYTRCTDGILFVIDSVDTERMEEAKMELMRTAKCPDNQGVPVLILANKQDL 143

Human   139 RNSLSLSEIEKLLAMGEL------------SSSTP------------------------------ 161
            .|:....|:||||.:.||            |.|:|
  Fly   144 PNACGAMELEKLLGLNELYNPVPNISMPSSSDSSPTINLIGCRVSNQSITDKSLEEKKESHLHSS 208

Human   162 ----------------------------------------------------------------- 161
                                                                             
  Fly   209 MIHIKPALESKDHNSTLSGGALTAFIYPQSHNNSAVLDQKNPQDVKNGFHNKKMNRSSSNSVQFR 273

Human   162 -WHLQPTCAIIGDGLKEGLEKLHDMIIKRRKMLRQQKK 198
             |::||||||.|:||:|||:.|:|||:||||:.:..|:
  Fly   274 GWYIQPTCAITGEGLQEGLDALYDMILKRRKINKSNKR 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARL4A	NP_005729.1	Arl4_Arl7	18..200	CDD:206719	116/289 (40%)
Arl4	NP_001245408.1	P-loop containing Nucleoside Triphosphate Hydrolases	24..311	CDD:476819	115/286 (40%)