Protein Alignment ACTR1A and Arp10

DIOPT Version :9

• Sequence 1: NP_005727.1
• Gene: ACTR1A / 10121
• HGNCID: 167
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_001285452.1
• Gene: Arp10 / 32969
• FlyBaseID: FBgn0031050
• Length: 378
• Species: Drosophila melanogaster
• Alignment Length: 404
• Identity: 83/404 - (20%)
• Similarity: 159/404 - (39%)
• Gaps: 87/404 - (21%)

Human     1 MESYDVIANQ--PVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGPKAE 63
            |..|:.:..:  |:|:|.|:...|.|||.:..|:...|..|       ||...
  Fly     1 MPIYESVMQEKPPIVLDIGTAYTKLGFAAEAYPRKIMPTEV-------VMTTT------------ 46

Human    64 EHRGLLSIRYPMEHGIVK---DWNDMERIWQYVYSKDQLQTF--------SEEHPVLLTEAPLNP 117
                          ||.|   |::..|.::..:.  |.|||.        .:|...:|.|.....
  Fly    47 --------------GIRKRLFDYDTPEELYDQLV--DFLQTIFFKHLLVSPKERKFVLVENVFGS 95

Human   118 RKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMR 182
            ...||..|.|.|..|:|.::......:::|......|.:|:|.|...|..:|::.|..:..:...
  Fly    96 TVLRETLARVLFVHFDVSSVLFVPVHLIALSTLAVPTALVVDVGYSETSVMPVFSGVQIMAAFKD 160

Human   183 IDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ------- 240
            ....|..:...::..|.:.|......:| .:::.||.|.|:::       |:|..||:
  Fly   161 QSYGGSAIHAEIKRQLVESGVKESLLTE-SVLEDIKVRTCFVT-------TMERAKARANGDENQ 217

Human   241 --------YYLPDGSTIEIGPSRFR--APELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLF 295
                    |.:.|...:...|...|  |.|::|.   ...|.:.:..:::.:|....:|:||.|.
  Fly   218 PTPAPDVDYIVSDNDAVIQVPGLLRESAYEIMFE---ASNERDSLPHLILRSILDCTLDVRRALV 279

Human   296 SNIVLSGGSTLFKGFGDRLLSEVKKLAPKD----------VKIR-ISAPQERLYSTWIGGSILAS 349
            .::.|.||.::.:|...||..|::.|..:|          ::.: .:|..::.::.|:||::..:
  Fly   280 ESVFLVGGGSMVQGLLARLRQELQHLLTEDPFYAERFHGELQFKFFNAVGKQNFTAWLGGALCGA 344

Human   350 LDTFKKMWVSKKEY 363
            .|..:...:.|:.|
  Fly   345 TDLIQTRSLVKETY 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTR1A	NP_005727.1	NBD_sugar-kinase_HSP70_actin	5..376	CDD:418402	81/400 (20%)
Arp10	NP_001285452.1	ACTIN	11..340	CDD:214592	77/374 (21%)
		NBD_sugar-kinase_HSP70_actin	12..367	CDD:302596	81/393 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900