Protein Alignment ACTR1A and Arp8

DIOPT Version :9

• Sequence 1: NP_005727.1
• Gene: ACTR1A / 10121
• HGNCID: 167
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_573251.1
• Gene: Arp8 / 32769
• FlyBaseID: FBgn0030877
• Length: 607
• Species: Drosophila melanogaster
• Alignment Length: 434
• Identity: 75/434 - (17%)
• Similarity: 148/434 - (34%)
• Gaps: 136/434 - (31%)

Human    71 IRYPMEHGIVKDWND-----------MERIWQYVYS---KDQLQTFSEEHPVLLTEAPLNPRKNR 121
            |.:|::.|.:...|:           :||||.|...   |..|:... .|..:|....:..|::.
  Fly   177 IHFPIQRGELNVHNEKGGSLQASMQHLERIWSYALEERLKIPLRKLG-THCAVLVVNDVYVRRHL 240

Human   122 ERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSIMRIDIA 186
            .....:..........|:...:|.|.:..|...|.|:|.|...|....|.:|.:...:.:|:...
  Fly   241 REFVTLLLRRLGFRRCFLVQDSVASTFGAGIGYGCVVDIGAQKTSIACIEDGISQLDARVRLSYG 305

Human   187 GRDVSRFLRLYLRKEGYDF------HSSSEFEIVKAIKERACYLSIN----PQKDETLETEKAQY 241
            |.|:.:.|.|.|||.|:.:      .|..:..::..:||:.|:|:.:    .:|...|.....|:
  Fly   306 GGDLDQVLLLLLRKCGFPYRECNVQESYVDAHLLDELKEKFCHLNASVCGAQEKHFNLRKHNGQW 370

Human   242 --YLPDGSTIEIGPSRFRAPELLF----------------------------------------- 263
              |     ||::|.....||..||
  Fly   371 LRY-----TIQVGDEALMAPLALFHTELLNITGRTKAVFTQQAVQDQYDCEDCFDAEYLKETGRK 430

Human   264 -------------------RPDL------------------------IGEESEG----------- 274
                               ||.|                        :|.::.|
  Fly   431 NGVRGGDILQLSTSAGYQPRPQLPVTADDEELIVVDQDETISNCQSQLGAQTAGGQMNSNGCYHN 495

Human   275 -------IHEVLVFAIQK-SDMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDVKIRIS 331
                   :.:.::.:|.: |..:.:|.:|.:|:|.|.|....|....|...:.:....:|.:.|.
  Fly   496 GQGLVLPLDQAIIQSINRLSSYETKRKMFGSILLVGSSAKLPGLAAWLEQRISQQVQSEVNVLIK 560

Human   332 APQERLYSTWIGGSILASLDTFKKMWVSKKEYEEDGARSIHRKT 375
            .....:.: |.|.:|::.|::.:::|:|:.:::..|.|.:..::
  Fly   561 GMDAGMVA-WKGAAIMSVLESARELWISQNDWQRHGLRVLRERS 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACTR1A	NP_005727.1	NBD_sugar-kinase_HSP70_actin	5..376	CDD:418402	75/434 (17%)
Arp8	NP_573251.1	NBD_sugar-kinase_HSP70_actin	202..603	CDD:302596	71/407 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5277
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810